Results 81 to 90 of about 1,545 (164)
Abstract 056 | Role of prohibitin isoforms in mitochondrial function with aging and exercise
Skeletal muscle is a highly metabolic and adaptable tissue that is reliant on an adequately-sized pool of healthy mitochondria to sustain its function (1,2).
Sabrina Champsi
doaj +1 more source
Journal of Diabetes Investigation, Volume 17, Issue 8, Page 1254-1256, August 2026.
Nozomi Kido, Shun‐ichiro Asahara
wiley +1 more source
The role and therapeutic potential of prohibitin in disease
Prohibitin 1 (PHB1), a pleiotropic protein in the cell, has been implicated in the regulation of proliferation, apoptosis, transcription, mitochondrial protein folding, and as a cell-surface receptor. This diverse array of functions of PHB1 is attributed to the cell type studied and its subcellular localization.
Theiss, Arianne L. +1 more
openaire +2 more sources
The mitochondrial complexome of Medicago truncatula
Legumes (Fabaceae, Leguminosae) are unique in their ability to carry out an elaborate endosymbiotic nitrogen fixation process with rhizobia proteobacteria.
Leonard Muriithi Kiirika +3 more
doaj +1 more source
Acne vulgaris is a very common disease of the pilosebaceous unit of the human skin. The pathological processes of acne are not fully understood. To gain further insight sebaceous follicular casts were extracted from 18 healthy and 20 acne-affected ...
Malene Bek-Thomsen +4 more
doaj +1 more source
Background Decidualization of endometrial cells is the prerequisite for embryo implantation and subsequent placenta formation and is induced by rising progesterone levels following ovulation.
Hailun Liu +7 more
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Role of Prohibitins as Guardians of mitochondrial homeostasis
Mitochondria are complex organelles critical to the maintenance of cellular homeostasis. Central to this regulation are Prohibitins (PHBs), a novel set of proteins involved in several mitochondrial quality control pathways, including protein folding, biogenesis, and mitophagy.
Sabrina Champsi, David A. Hood
openaire +2 more sources
An unconventional autophagic pathway that inhibits ATP secretion during apoptotic cell death
Mobilisation of Damage-Associated Molecular Patterns (DAMPs) determines the immunogenic properties of apoptosis, but the mechanisms that control DAMP exposure are still unclear.
Elena Terraza-Silvestre +7 more
doaj +1 more source
Structural basis for prohibitin-mediated regulation of mitochondrial m-AAA protease
Mitochondrial function critically depends on protein quality control systems, with the m-AAA protease playing a key role at the inner mitochondrial membrane (IMM).
Dingyi Luo +6 more
doaj +1 more source
Prohibitin as a novel autoantigen in rheumatoid arthritis.
The aim of this study was to verify whether prohibitin is a novel autoantigen in rheumatoid arthritis.First, recombinant human prohibitin (rhPHB) protein was cloned, expressed, and purified. Then the anti-prohibitin autoantibodies were detected by western blotting by using rhPHB protein to incubate sera from patients with rheumatoid arthritis (RA ...
Shi, Li-Li +6 more
openaire +2 more sources

