Results 91 to 100 of about 1,728 (183)
Functional characterization of prohibitins by conditional inactivation in the mouse
, 2008 Prohibitins comprise an evolutionary conserved and ubiquitously expressed family of membrane proteins implicated in a large variety of cellular processes. Large assemblies of PHB1 and PHB2 subunits are localized in the inner membrane of mitochondria, but
Merkwirth, Carsten
core
Role of prohibitins for proteolysis in yeast and murine mitochondria
, 2006 Prohibitins, Phb1 and Phb2, are evolutionary conserved proteins with diverse cellular localization and different functions. In yeast, prohibitins form a high molecular weight complex in the inner mitochondrial membrane which physically interacts with the
Metodiev, Metodi Dimitrov
core
The role and therapeutic potential of prohibitin in disease
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2011 Prohibitin 1 (PHB1), a pleiotropic protein in the cell, has been implicated in the regulation of proliferation, apoptosis, transcription, mitochondrial protein folding, and as a cell-surface receptor. This diverse array of functions of PHB1 is attributed to the cell type studied and its subcellular localization.
Theiss, Arianne L. +1 more
openaire +2 more sources
Characterization of the genetic interactome of prohibitins in S. cerevisiae
, 2009 Prohibitins comprise an evolutionary conserved and ubiquitously expressed family of membrane proteins that is essential for development in higher eukaryotes.
Osman, Christof
core
The complexities of respiratory chain biogenesis and maintenance in yeast mitochondria
Protein Science, Volume 35, Issue 4, April 2026.Abstract Mitochondrial oxidative phosphorylation is the most efficient way of energy conversion for eukaryotic cells. It is executed by a series of high‐molecular weight enzyme complexes in the inner mitochondrial membrane that were acquired during endosymbiosis at the root of eukaryotic evolution.
Andreas Carlström +2 more
wiley +1 more source
Abstract 056 | Role of prohibitin isoforms in mitochondrial function with aging and exercise
European Journal of Translational MyologySkeletal muscle is a highly metabolic and adaptable tissue that is reliant on an adequately-sized pool of healthy mitochondria to sustain its function (1,2).
Sabrina Champsi
doaj +1 more source
, 2006 The generation of cellular energy depends on the coordinated assembly of nuclear and mitochondrial-encoded proteins into multisubunit respiratory chain complexes in the inner membrane of mitochondria.
Claudia Wilmes +7 more
core +1 more source
The mitochondrial complexome of Medicago truncatula
Frontiers in Plant Science, 2013 Legumes (Fabaceae, Leguminosae) are unique in their ability to carry out an elaborate endosymbiotic nitrogen fixation process with rhizobia proteobacteria.
Leonard Muriithi Kiirika +3 more
doaj +1 more source
Role of Prohibitins as Guardians of mitochondrial homeostasis
MitochondrionMitochondria are complex organelles critical to the maintenance of cellular homeostasis. Central to this regulation are Prohibitins (PHBs), a novel set of proteins involved in several mitochondrial quality control pathways, including protein folding, biogenesis, and mitophagy.
Sabrina Champsi, David A. Hood
openaire +2 more sources
PLoS ONE, 2014 Acne vulgaris is a very common disease of the pilosebaceous unit of the human skin. The pathological processes of acne are not fully understood. To gain further insight sebaceous follicular casts were extracted from 18 healthy and 20 acne-affected ...
Malene Bek-Thomsen +4 more
doaj +1 more source