Results 101 to 110 of about 1,827 (179)

The role and therapeutic potential of prohibitin in disease

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2011
Prohibitin 1 (PHB1), a pleiotropic protein in the cell, has been implicated in the regulation of proliferation, apoptosis, transcription, mitochondrial protein folding, and as a cell-surface receptor. This diverse array of functions of PHB1 is attributed to the cell type studied and its subcellular localization.
Theiss, Arianne L., Sitaraman, Shanthi V.   +1 more
openaire   +2 more sources

PHB3 Maintains Root Stem Cell Niche Identity through ROS-Responsive AP2/ERF Transcription Factors in Arabidopsis

Cell Reports, 2018
Summary: The root stem cell niche, which is composed of four mitotically inactive quiescent center (QC) cells and the surrounding actively divided stem cells in Arabidopsis, is critical for growth and root development.
Xiangpei Kong, Huiyu Tian, Qianqian Yu, Feng Zhang, Rong Wang, Shan Gao, Wenhong Xu, Jiajia Liu, Eilon Shani, Chunxiang Fu, Gongke Zhou, Liangran Zhang, Xiansheng Zhang, Zhaojun Ding   +13 more
doaj   +1 more source

Formation of Membrane-bound Ring Complexes by Prohibitins in Mitochondria

, 2004
Prohibitins comprise a remarkably conserved protein family in eukaryotic cells with proposed functions in cell cycle progression, senescence, apoptosis, and the regulation of mitochondrial activities.
Model, K., Model, Kirstin, Langer, Thomas, Tatsuta, T., Langer, T., Tatsuta, Takashi   +5 more
core   +1 more source

Abstract 056 | Role of prohibitin isoforms in mitochondrial function with aging and exercise

European Journal of Translational Myology
Skeletal muscle is a highly metabolic and adaptable tissue that is reliant on an adequately-sized pool of healthy mitochondria to sustain its function (1,2).
Sabrina Champsi
doaj   +1 more source

The mitochondrial complexome of Medicago truncatula

Frontiers in Plant Science, 2013
Legumes (Fabaceae, Leguminosae) are unique in their ability to carry out an elaborate endosymbiotic nitrogen fixation process with rhizobia proteobacteria.
Leonard Muriithi Kiirika, Christof eBehrens, Hans-Peter eBraun, Frank eColditz   +3 more
doaj   +1 more source

Recent advances in pancreatic β‐cell dysfunction in type 2 diabetes mellitus: Intracellular stress and dedifferentiation

Journal of Diabetes Investigation, Volume 17, Issue 8, Page 1254-1256, August 2026.
Nozomi Kido, Shun‐ichiro Asahara
wiley   +1 more source

Proteome analysis of human sebaceous follicle infundibula extracted from healthy and acne-affected skin.

PLoS ONE, 2014
Acne vulgaris is a very common disease of the pilosebaceous unit of the human skin. The pathological processes of acne are not fully understood. To gain further insight sebaceous follicular casts were extracted from 18 healthy and 20 acne-affected ...
Malene Bek-Thomsen, Hans B Lomholt, Carsten Scavenius, Jan J Enghild, Holger Brüggemann   +4 more
doaj   +1 more source

Progesterone-induced progesterone receptor membrane component 1 rise-to-decline changes are essential for decidualization

Reproductive Biology and Endocrinology
Background Decidualization of endometrial cells is the prerequisite for embryo implantation and subsequent placenta formation and is induced by rising progesterone levels following ovulation.
Hailun Liu, André Franken, Alexandra P. Bielfeld, Tanja Fehm, Dieter Niederacher, Zhongping Cheng, Hans Neubauer, Nadia Stamm   +7 more
doaj   +1 more source

An unconventional autophagic pathway that inhibits ATP secretion during apoptotic cell death

Nature Communications
Mobilisation of Damage-Associated Molecular Patterns (DAMPs) determines the immunogenic properties of apoptosis, but the mechanisms that control DAMP exposure are still unclear.
Elena Terraza-Silvestre, Raquel Villamuera, Julia Bandera-Linero, Michal Letek, Daniel Oña-Sánchez, Cristina Ramón-Barros, Clara Moyano-Jimeno, Felipe X. Pimentel-Muiños   +7 more
doaj   +1 more source

CaMK IV phosphorylates prohibitin 2 and regulates prohibitin 2-mediated repression of MEF2 transcription

Cellular Signalling, 2011
Prohibitin 2 (PHB2) is an evolutionarily conserved and ubiquitously expressed multifunctional protein which is present in various cellular compartments including the nucleus. However, mechanisms underlying various functions of PHB2 are not fully explored yet.
Sun, Luguo, Cao, Xia, Liu, Bin, Huang, Honglan, Wang, Xu, Sui, Liyan, Yin, Weimin, Ma, Kewei   +7 more
openaire   +2 more sources