Results 31 to 40 of about 24,694 (257)

Reactive extrusion mechanism, mechanical and tribological behavior of fiber reinforced polyamide 66 with added carbodiimide

Materials & Design, 2020
In this study, the reactive extrusion mechanism of fiber-reinforced polyamide 66 materials with added carbodiimide was clarified, and the mechanical and tribological properties of the materials were evaluated.
Takeshi Kunishima, Takanori Kurokawa, Hirokazu Arai, Vincent Fridrici, Phillippe Kapsa   +4 more
doaj   +1 more source

Compatibilization of Poly(Lactic Acid) (PLA)/Plasticized Cellulose Acetate Extruded Blends through the Addition of Reactively Extruded Comb Copolymers

Molecules, 2021
In the perspective of producing a rigid renewable and environmentally friendly rigid packaging material, two comb-like copolymers of cellulose acetate (AC) and oligo(lactic acid) OLA, feeding different percentages of oligo(lactic acid) segments, were ...
Maria-Beatrice Coltelli, Norma Mallegni, Sara Rizzo, Stefano Fiori, Francesca Signori, Andrea Lazzeri   +5 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Chemical Modification of Cellulose Using a Green Route by Reactive Extrusion with Citric and Succinic Acids

Polysaccharides, 2022
Cellulose is a natural, unbranched, and fibrous homopolymer that is a major component in several agroindustrial residues. The aim of this study was to extract cellulose from oat hulls and then to modify it using a green route to obtain esterified ...
Jéssica Fernanda Pereira, Beatriz Marjorie Marim, Suzana Mali   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Oat fibers modification by reactive extrusion with alkaline hydrogen peroxide

Polímeros
The modification of lignocellulosic fibers can enhance their interaction with other materials and alkaline hydrogen peroxide (AHP) is a reagent widely used to promote such modification.
Melina Aparecida Plastina Cardoso, Gizilene Maria Carvalho, Fabio Yamashita, Suzana Mali, Juliana Bonametti Olivato, Maria Victoria Eiras Grossmann   +5 more
doaj   +1 more source

Preparation and Characteristic of PC/PLA/TPU Blends by Reactive Extrusion

Advances in Materials Science and Engineering, 2015
To overcome the poor toughness of PC/PLA blends due to the intrinsic properties of materials and poor compatibility, thermoplastic urethane (TPU) was added to PC/PLA blends as a toughener; meantime, catalyst di-n-butyltin oxide (DBTO) was also added for ...
Yueyun Zhou, Lifa Luo, Wenyong Liu, Guangsheng Zeng, Yi Chen   +4 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source