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[Reactive oxygen and nitrogen species].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2012Reactive oxygen and nitrogen species (ROS and RNS respectively) play an important role in the proper functioning of many cellular processes. Generation of reactive oxygen species is an integral part of aerobic metabolism of cells. Their overproduction and subsequent oxidative stress occurs during pathogenesis of many diseases.
Mateusz, Ługowski +3 more
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Reactive Oxygen and Reactive Nitrogen Species in the Lung
2000Reactive oxygen species (ROS) and reactive nitrogen species (RNS) have been implicated as contributing to the pathogenesis of a broad spectrum of diseases [1, 2]. Historically, oxygen free radicals were primarily considered to be aggressive species, indeed the superoxide (O 2 .- theory of oxygen toxicity is based on this hypothesis, (reviewed in 3 ...
Gregory J. Quinlan, Nicholas J. Lamb
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Interaction of surfactant mixtures with reactive oxygen and nitrogen species
Journal of Applied Physiology, 1995Increased concentrations of partially reduced oxygen and nitrogen reactive species damage the alveolar epithelium and either cause or exacerbate surfactant deficiency. For this reason, there is a quest to identify surfactant replacement mixtures, which in addition to repleting depleted surfactant stores can also reduce the steady-state concentrations ...
J, Cifuentes +5 more
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Cell signaling by reactive nitrogen and oxygen species in atherosclerosis
Free Radical Biology and Medicine, 2000The production of reactive oxygen and nitrogen species has been implicated in atherosclerosis principally as means of damaging low-density lipoprotein that in turn initiates the accumulation of cholesterol in macrophages. The diversity of novel oxidative modifications to lipids and proteins recently identified in atherosclerotic lesions has revealed ...
R P, Patel +5 more
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Reactive oxygen and nitrogen species during viral infections
Free Radical Research, 2014Oxygen and nitrogen radicals are frequently produced during viral infections. These radicals are not only a physiological mechanism for pathogen clearance but also result in many pathological consequences. Low concentrations of radicals can promote viral replication; however, high concentrations of radicals can also inhibit viral replication and are ...
C. G. Molteni +2 more
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Damage to proteins by reactive oxygen and reactive nitrogen species
2000Abstract The aromatic amino acids of proteins, e.g. phenylalanine and tyrosine, are particularly susceptible to oxidative modification and, therefore, provide useful evidence of oxidative damage in biological systems.
G J Quinlan, J M C Gutteridge
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Nanotechnology for Electroanalytical Biosensors of Reactive Oxygen and Nitrogen Species
The Chemical Record, 2017AbstractOver the past several decades, nanotechnology has contributed to the progress of biomedicine, biomarker discovery, and the development of highly sensitive electroanalytical / electrochemical biosensors for in vitro and in vivo monitoring, and quantification of oxidative and nitrosative stress markers like reactive oxygen species (ROS) and ...
Rajesh, Seenivasan +3 more
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Analysis of Microglial Production of Reactive Oxygen and Nitrogen Species
2013Reactive oxygen and nitrogen species are both regulators and effectors of microglial activation, and assays of these oxidants can be used as a measure of acute and chronic activation of microglial cells. Here we describe quick methods to assess the production of superoxide, hydrogen peroxide, nitric oxide, and peroxynitrite by microglia.
Urte, Neniskyte, Guy C, Brown
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Control of Auxin Transport by Reactive Oxygen and Nitrogen Species
2013Libro: Polar Auxin ...
Fernández Marcos, María +4 more
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Reactive oxygen and nitrogen species in normal physiological processes
Acta Physiologica, 2009AbstractReactive oxygen species (ROS) and reactive nitrogen species have generally been considered as being highly reactive and cytotoxic molecules. Besides their noxious effects, ROS participate in physiological processes in a carefully regulated manner. By way of example, microbicidal ROS are produced in professional phagocytes, ROS function as short‐
J, Pourova +3 more
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