Results 51 to 60 of about 242,902 (286)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Considerations of the importance of redox state for reactive nitrogen species action [PDF]
, 2019 Nitric oxide (NO) and other reactive nitrogen species (RNS) are immensely important signalling molecules in plants, being involved in a range of physiological responses.
Hancock, John T.
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Extracellular production of reactive oxygen species in response to abiotic stress in seeds [PDF]
, 2009 Reactive oxygen species (ROS), such as superoxide (O2 •‾), hydrogen peroxide (H2O2), singlet oxygen (1O2) and the hydroxyl radical (•OH) can damage essential biomolecules including nucleic acids, proteins and lipids, causing damage to various ...
Roach, T.
core
Oxidative Stress in Renal Health
AntioxidantsOxidative stress is caused by the increase in reactive oxygen species (ROS) and reactive nitrogen species (RNS) inside cells [...]
Ana Cristina Simões e Silva
doaj +1 more source
Roles of Toll-Like Receptors in Nitroxidative Stress in Mammals
Cells, 2019 Free radicals are important antimicrobial effectors that cause damage to DNA, membrane lipids, and proteins. Professional phagocytes produce reactive oxygen species (ROS) and reactive nitrogen species (RNS) that contribute towards the destruction of ...
Yao Li +3 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Influence of reactive oxygen and nitrogen species on udder health and milk quality
Revista do Instituto de Latícinios Cândido Tostes, 2022 Mastitis is considered the most common disease affecting dairy herds. It causes relevant economic losses to producers and decreases milk quality and yield for the dairy industry.
Renison Teles Vargas +9 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
, 2019 Infertility is a significant global health problem that currently affects one of six couples in reproductive age. The quality of male reproductive cells dramatically decreased over the last years and almost every aspect of modern life additionally worsen
Korać, Bato +9 more
core +1 more source