Results 71 to 80 of about 242,902 (286)

The glutathione biosynthetic pathway of Plasmodium is essential for mosquito transmission [PDF]

, 2009
1Infection of red blood cells (RBC) subjects the malaria parasite to oxidative stress. Therefore, efficient antioxidant and redox systems are required to prevent damage by reactive oxygen species. Plasmodium spp.
Vega-Rodríguez Joel, Franke-Fayard Blandine, Coppens Isabelle, Waters Andrew P., Dinglasan, R.R., Andrew P. Waters, Joel Vega-Rodríguez, Rhoel R. Dinglasan, Jacobs-Lorena Marcelo, José F Rodríguez-Orengo, Jacobs-Lorena, M., Rodríguez-Orengo José F., Blandine Franke-Fayard, Chris J. Janse, Vega-Rodriguez, J., Isabelle Coppens, José F. Rodríguez-Orengo, Serrano Adelfa E., Adelfa E. Serrano, Janse, C.J., Serrano, A.E., Rhoel R Dinglasan, Prakash Srinivasan, Waters, A., Adelfa E Serrano, Marcelo Jacobs-Lorena, Pastrana-Mena Rebecca, Janse Chris J., Chris J Janse, Dinglasan Rhoel R., Rodriguez-Orengo, J.F., Srinivasan, P., Pastrana-Mena, R., Rebecca Pastrana-Mena, Franke-Fayard, B., Andrew P Waters   +35 more
core   +2 more sources

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Impact of surface structure and feed gas composition on Bacillus subtilis endospore inactivation during direct plasma treatment

Frontiers in Microbiology, 2015
This study investigated the inactivation efficiency of cold atmospheric pressure plasma treatment on Bacillus subtilis endospores dependent on the used feed gas composition and on the surface, the endospores were attached on.
Christian eHertwig, Veronika eSteins, Kai eReineke, Antje eRademacher, Michael eKlocke, Cornelia eRauh, Oliver eSchlüter   +6 more
doaj   +1 more source

Silicon Confers Soybean Resistance to Salinity Stress Through Regulation of Reactive Oxygen and Reactive Nitrogen Species

Frontiers in Plant Science, 2020
Salt stress is one of the major abiotic stressors that causes huge losses to the agricultural industry worldwide. Different strategies have been adopted over time to mitigate the negative impact of salt stress on plants and reclaim salt-affected lands ...
Yong Suk Chung, Ki-Seung Kim, Muhammad Hamayun, Yoonha Kim   +3 more
doaj   +1 more source

DNA damage and reactive nitrogen species are barriers to Vibrio cholerae colonization of the infant mouse intestine. [PDF]

PLoS Pathogens, 2011
Ingested Vibrio cholerae pass through the stomach and colonize the small intestines of its host. Here, we show that V. cholerae requires at least two types of DNA repair systems to efficiently compete for colonization of the infant mouse intestine. These
Bryan W Davies, Ryan W Bogard, Nicole M Dupes, Tyler A I Gerstenfeld, Lyle A Simmons, John J Mekalanos   +5 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Reactive Nitrogen Species In Cellular Signaling

, 2015
The transduction of cellular signals occurs through the modification of target molecules. Most of these modifications are transitory, thus the signal transduction pathways can be tightly regulated.
Franco, Maria C., Adams, Levi, Estevez, Alvaro G.   +2 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

High‐Resolution Corrosion Fingerprinting of Alloy Libraries via Microdroplet Spectroelectrochemistry

Advanced Engineering Materials, EarlyView.
Ionic‐liquid microdroplet spectroelectrochemistry enables stable, localized electrochemical measurements over extended timescales. By coupling impedance spectroscopy, wetting analysis, finite‐element simulations, and operando Raman spectroscopy, it disentangles geometrical and electrochemical effects, opening new opportunities for rapid corrosion ...
Ekaterina Kurchavova, Oumaïma Gharbi, Mireille Turmine, Vincent Vivier   +3 more
wiley   +1 more source

Effects of low temperature plasmas and plasma activated waters on Arabidopsis thaliana germination and growth. [PDF]

PLoS ONE, 2018
Two plasma devices at atmospheric pressure (air dielectric barrier discharge and helium plasma jet) have been used to study the early germination of Arabidopsis thaliana seeds during the first days. Then, plasma activated waters are used during the later
Maxime Bafoil, Achraf Jemmat, Yves Martinez, Nofel Merbahi, Olivier Eichwald, Christophe Dunand, Mohammed Yousfi   +6 more
doaj   +1 more source