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Reactive oxygen species in mechanotransduction

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2004
a randomized clinical trial by the Acute Respiratory Distress Syndrome Network ([1][1]) demonstrated a 22% reduction in mortality in patients by reducing the tidal volume for mechanical ventilation from the conventional setting of 12 ml/kg to a lower setting of 6 ml/kg.
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Reactive Oxygen Species

1994
It has been known for over a century that the combination of light, oxygen, and several dyes leads to the oxidation of organic substrates. Photooxygenation reactions are known to involve active forms of oxygen, formed as a direct consequence of the absorption of light.
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Reactive Oxygen Species as Mediators in Asthma

Pulmonary Pharmacology & Therapeutics, 2001
This review describes production and effects of reactive oxygen species (ROS) on airway function. ROS are important in many physiological processes but can also have detrimental effects on airway cells and tissues when produced in high quantities or during the absence of sufficient amounts of anti-oxidants.
Frans P. Nijkamp, Paul A.J. Henricks
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Oxidative Stress and Reactive Oxygen Species

2005
This article discusses different aspects concerning classification/nomenclature, biochemical properties and pathophysiological roles of reactive oxygen species (ROS) which are pivotal to interpret the concept of oxidative stress. In vitro studies in both the prokaryotes and eukaryotes clearly demonstrate that exogenous or constitutive and inducible ...
GALLI, Francesco   +5 more
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Chemistry of Reactive Oxygen Species [PDF]

open access: possible, 1985
Oxidation is one of the most significant causes of foodstuff deterioration. It can lead to rancidity, off-flavor and -color, deterioration of texture, and other damage. Toxic materials may also result from the oxidation of naturally occurring substances (Pryor 1984). For example, cholesterol epoxides and hydroperoxides are thought to be carcinogenic or
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Reactive Oxygen Species Signaling in Plants

Antioxidants & Redox Signaling, 2006
The evolution of aerobic metabolism such as respiration and photosynthesis resulted in the generation of reactive oxygen species (ROS). A common property of all ROS types is that they can cause oxidative damage to proteins, DNA, and lipids. This toxicity of ROS explains the evolution of complex arrays of nonenzymatic and enzymatic detoxification ...
Heribert Hirt   +2 more
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Reactive oxygen species are NOXious for neurons

Nature Neuroscience, 2009
Mitochondria are considered to be the main source of reactive oxygen species during glutamate excitotoxicity. Data now support a prominent role in this process for NADPH oxidase, the enzyme that neutrophils use to kill bacteria.
Demaurex N, SCORRANO, LUCA
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Reactive oxygen species in hypertension

Nature Reviews Cardiology
Hypertension is a leading risk factor for stroke, heart disease and chronic kidney disease. Multiple interacting factors and organ systems increase blood pressure and cause target-organ damage. Among the many molecular elements involved in the development of hypertension are reactive oxygen species (ROS), which influence cellular processes in systems ...
Livia L. Camargo   +3 more
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Mitochondrial metabolism of reactive oxygen species

Mitochondrion, 2013
For a long time mitochondria have mainly been considered for their role in the aerobic energy production in eukaryotic cells, being the sites of the oxidative phosphorylation, which couples the electron transfer from respiratory substrates to oxygen with the ATP synthesis.
VENDITTI, PAOLA   +2 more
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Preeclampsia and Reactive Oxygen Species [PDF]

open access: possibleThe Indian Journal of Pediatrics, 2018
Shikha Rani, Deepak Chawla
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