Results 41 to 50 of about 2,976 (300)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Fast Transient Hybrid Neuro Fuzzy Controller for STATCOM During Unbalanced Voltage Sags [PDF]

AUT Journal of Electrical Engineering, 2018
A static synchronous compensator (STATCOM) is generally used to regulate voltage and improve transient stability in transmission and distribution networks. This is achieved by controlling reactive power exchange between STATCOM and the grid.
R. Zaheri Abdevand, A. khoshsaadat, J. Shokrollah Moghani, M. Abedi   +3 more
doaj   +1 more source

DOWNHOLE REACTIVE POWER COMPENSATION

Oil and Gas Studies, 2015
The authors provide a method for compensation of the reactive power inside a well. In the environment Matlab/ Simylink a model was developed of the site of the electrical centrifugal pump unit power supply from the transformer substation. A comparison is made of the proposed method of downhole reactive power compensation with the existing method.
V. A. Kopyrin, V. A. Iordan, O. V. Smirnov   +2 more
openaire   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez, Alejandro F. Manchón‐Gordón, Antonio Vidal‐Crespo, Rafael Caballero‐Flores, Jhon J. Ipus, Clara F. Conde   +5 more
wiley   +1 more source

Design of fractional evolutionary processing for reactive power planning with FACTS devices

Scientific Reports, 2021
Reactive power dispatch is a vital problem in the operation, planning and control of power system for obtaining a fixed economic load expedition. An optimal dispatch reduces the grid congestion through the minimization of the active power loss.
Yasir Muhammad, Rizwan Akhtar, Rahimdad Khan, Farman Ullah, Muhammad Asif Zahoor Raja, J. A. Tenreiro Machado   +5 more
doaj   +1 more source

Study on resonance characteristic of continuous co‐phase traction power supply system

IET Generation, Transmission & Distribution, 2023
In order to solve the power quality problems and eliminate the neutral sections in the railway, the implementation of the continuous co‐phase traction power supply system (CCTPSS) is the development trend of the future. However, various parameters of the
Fan Zhong, Shaofeng Xie
doaj   +1 more source

THE ROLE OF STATIC VAR COMPENSATOR AT REACTIVE POWER COMPENSATION

European Journal of Technic, 2020
The need for electricity is increasing and the cost of energy generation is arising. For this reason, it is important to use the generated energy in good quality, safely and efficiently. Reactive power compensation is one of the most effective application to reduce transmission losses, prevent voltage drops, prevent consumers from paying for reactive ...
KOCAMAN, Behçet, ABUT, Nurettin
openaire   +3 more sources