Results 21 to 30 of about 2,835,706 (332)

Normal aging induces A1-like astrocyte reactivity

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance In aging, the brain becomes vulnerable to injury and cognitive function declines, but the mechanisms responsible are unknown. Astrocytes, the most abundant class of glial cells, are vital for the proper function of the central nervous system,
L. Clarke, S. A. Liddelow, C. Chakraborty, Alexandra E. Münch, M. Heiman, B. Barres   +5 more
semanticscholar   +1 more source

Chemical Basis of Reactive Oxygen Species Reactivity and Involvement in Neurodegenerative Diseases

International Journal of Molecular Sciences, 2019
Increasing numbers of individuals suffer from neurodegenerative diseases, which are characterized by progressive loss of neurons. Oxidative stress, in particular, the overproduction of Reactive Oxygen Species (ROS), play an important role in the ...
F. Collin
semanticscholar   +1 more source

Adsorption Thermodynamic and Kinetic Studies of Methyl Orange onto Sugar Scum Powder as a Low-Cost Inorganic Adsorbent

Journal of Chemistry, 2020
In the present study, batch adsorption experiments were carried out to investigate the removal of methyl orange (MO) from aqueous solution using sugar scum powder as an effective inorganic adsorbent which is a cheap precursor and abundant.
Y. El maguana, N. Elhadiri, M. Benchanaa, R. Chikri   +3 more
doaj   +1 more source

Cardioprotective Antioxidant and Anti-Inflammatory Mechanisms Induced by Intermittent Hypobaric Hypoxia

Antioxidants, 2022
More than 80 million people live and work (in a chronic or intermittent form) above 2500 masl, and 35 million live in the Andean Mountains. Furthermore, in Chile, it is estimated that 100,000 people work in high-altitude shifts, where stays in the ...
Alejandro González-Candia, Alejandro A. Candia, Adolfo Paz, Fuad Mobarec, Rodrigo Urbina-Varela, Andrea del Campo, Emilio A. Herrera, Rodrigo L. Castillo   +7 more
doaj   +1 more source

Life events and acute cardiovascular reactions to mental stress: a cohort study [PDF]

, 2005
Objective: This study addressed the issue of whether frequent exposure to life events is associated with aggravation or blunting of cardiovascular reactions to acute mental stress.
Carroll, Douglas, Phillips, Anna C., Ring, Christopher, Sweeting, Helen, West, Patrick   +4 more
core   +1 more source

α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease

Nature Communications, 2020
A diagnosis of motor Parkinson’s disease (PD) is preceded by a prolonged premotor phase with accumulating neuronal damage. Here we examined the temporal relation between α-synuclein (α-syn) T cell reactivity and PD.
C. L. Lindestam Arlehamn, Rekha Dhanwani, J. Pham, R. Kuan, A. Frazier, Juliana Rezende Dutra, E. Phillips, S. Mallal, M. Roederer, K. Marder, A. Amara, D. Standaert, J. Goldman, I. Litvan, Bjoern Peters, D. Sulzer, A. Sette   +16 more
semanticscholar   +1 more source

Regioselective One-Pot Synthesis, Biological Activity and Molecular Docking Studies of Novel Conjugates N-(p-Aryltriazolyl)-1,5-benzodiazepin-2-ones as Potent Antibacterial and Antifungal Agents

Molecules, 2022
Novel 1,2,3-triazolo-linked-1,5-benzodiazepinones were designed and synthesized via a Cu(I)-catalyzed 1,3-dipolar alkyne-azide coupling reaction (CuAAC).
Asma Nsira, Hasan Mtiraoui, Sami Chniti, Hanan Al-Ghulikah, Rafik Gharbi, Moncef Msaddek   +5 more
doaj   +1 more source

Are Large Physiological Reactions to Acute Psychological Stress Always Bad for Health? [PDF]

, 2009
How we react physiologically to stress has long been considered to have implications for our health. There is now persuasive evidence that individuals who show large cardiovascular reactions to stress are at increased risk of developing cardiovascular ...
Acheson, Adolphs, Allen, Al’Absi, Al’Absi, Al’Absi, Anisman, Bachen, Barch, Barnett, Bechara, Beck, Blair, Bosch, Bosch, Bosch, Brydon, Buchanan, Cacioppo, Caldji, Carney, Carroll, Carroll, Carroll, Carroll, Carroll, Carroll, Carroll, Carroll, Caspi, Critchley, Cuthbert, Damasio, Damasio, De Boer, De Boer, Dhabhar, Dhabhar, Ditto, Drummond, Edwards, Edwards, Edwards, Edwards, Enoch, Everson, Everson, Fredrikson, Gagnon, Georgiades, Gianaros, Gianaros, Girdler, Glahn, Goldman, Grassi, Hemingway, Idler, Ishiguro, Kanitz, Kapuku, Kario, Kario, Kibler, Kirschbaum, Kirschbaum, Kirschbaum, Krantz, Lazarus, Leor, Lesch, Light, Lipsky, Liu, Lovallo, Lovallo, Lovallo, Lovallo, Lovallo, Lovallo, Lovallo, Lovallo, Lowe, Lynch, Maier, Manuck, Manuck, Manuck, Manuck, Markovitz, Matthews, Matthews, Meaney, Meaney, Meisel, Mesulam, Millan, Miller, Mischler, Moss, Muldoon, Murdison, Naqvi, Newman, Obrist, Panknin, Patterson, Patterson, Phillips, Phillips, Phillips, Phillips, Phillips, Plotsky, Pomerleau, Rohleder, Rolls, Roy, Schwartz, Sheffield, Silberman, Sims, Smith, Smolka, Sorocco, Straneva, Tentolouris, Tentolouris, Tofler, Treiber, Treiber, Trichopoulos, Tuchscherer, Turner, Ungerleider, Vandenbergh, Welle, Williams, Williams, Witte, Wulsin, York, Zgraggen, Zigmond, Zubieta   +144 more
core   +2 more sources

Cardiovascular and cortisol reactions to acute psychological stress and cognitive ability in the Dutch Famine Birth Cohort Study [PDF]

, 2011
Objective: Recently, in analyses of data from a large community sample, negative cross-sectional and prospective associations between cardiac stress reactivity and obesity were observed.
al'Absi, al'Absi, al'Absi, Backs, Bakker, Balanos, Barnett, Blair, Busato, Carroll, Carroll, Carroll, Carroll, Carroll, Carroll, Carroll, Deary, DeGangi, deRooij, deRooij, deRooij, Domes, Duschek, Dweck, Elias, Elias, Everson, Georgiades, Ginty, Girdler, Heaney, Heim, Kapuku, Koo-Loeb, Launer, Lovallo, Lovallo, Lupien, Lynch, Markovitz, Matthews, Matthews, McClelland, Murdison, Newman, Novak, Painter, Panknin, Phillips, Phillips, Phillips, Pintrich, Pruessner, Rabbitt, Ravelli, Robbins, Rottenberg, Roy, Salomon, Singh-Manoux, Sloan, Waldstein, Waldstein, Waldstein, Wolf, Wood, Wright, York   +67 more
core   +1 more source

Vitrimers: directing chemical reactivity to control material properties

Chemical Science, 2020
The development of more sustainable materials with a prolonged useful lifetime is a key requirement for a transition towards a more circular economy.
M. Guerre, C. Taplan, Johan M. Winne, Filip E. Du Prez   +3 more
semanticscholar   +1 more source