Results 51 to 60 of about 3,474,148 (258)

Effect of proofreading on mechanics and structure of writing--grades four, five, six [PDF]

open access: yes, 1956
Thesis (M.A.)--Boston ...
Alpert, Faith   +8 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Low-Cost Spinning Disk Confocal Microscopy with a 25-Megapixel Camera

open access: yesSensors
Spinning disk confocal microscopy enables fast optical sectioning with low phototoxicity but is often inaccessible due to high hardware costs. We present a lower-cost solution using a 25-megapixel machine vision CMOS camera and a custom-built spinning ...
Guy M. Hagen   +4 more
doaj   +1 more source

Assembling La nueva novela: Juan Luis Martínez and a Material Poetics of Relation

open access: yesLatin American Research Review, 2017
This article considers 'La nueva novela', a strange book-object assembled by twentieth-century Chilean poet Juan Luis Martínez, in light of Édouard Glissant’s “poetics of relation” and Manuel DeLanda’s elaboration of “assemblage theory.” By bringing ...
Rebecca Kosick
doaj   +1 more source

Year 1 phonics screening check : framework for the pilot in 2011 [PDF]

open access: yes, 2011
"For the development of the year 1 phonics screening check" -- front ...

core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Re/position? "Tres Marías y una Rosa" three decades to address the resistance

open access: yesRevista Chilena de Literatura, 2010
The present work explores the conditions and repercussions of staging anew an emblematic play of the dictatorship era in Chile: "Tres Marías y una Rosa," three decades after that period, and without significant modifications.
Yael Zaliasnik
doaj  

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