Results 31 to 40 of about 4,178,128 (285)
Identifying Copy Number Variations based on Next Generation Sequencing Data by a Mixture of Poisson Model [PDF]
, 2010 Next generation sequencing (NGS) technologies have profoundly impacted biological research and are becoming more and more popular due to cost effectiveness and their speed.
Andreas Mayr +4 more
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Frontiers in Pharmacology, 2016 1.AbstractInterest is increasing in the development of non-animal methods for toxicological evaluations. These methods are however, particularly challenging for complex toxicological endpoints such as repeated dose toxicity.
Monika Batke +8 more
doaj +1 more source
Frontiers in Pharmacology, 2018 This study compares the accuracy of (Q)SAR/read-across predictions with the experimental variability of chronic lowest-observed-adverse-effect levels (LOAELs) from in vivo experiments.
Christoph Helma +7 more
doaj +1 more source
Current Research in Toxicology, 2021 There is a large body of information on testing of chemicals for skin sensitization in the murine local lymph node assay (LLNA), in which potency is quantified by the EC3 value, derived from dose-response data.
David W. Roberts
doaj +1 more source
Phonetic convergence in temporal organization during shadowed speech [PDF]
, 2020 The goal of this study was to examine phonetic convergence (when one imitates the phonetic characteristics of another talker) in various measures of temporal organization during shadowed speech across different American English dialects.
Gonzalez, Roberto
core
Brain matters…in social sciences [PDF]
, 2016 Here we offer a general introduction to cognitive neuroscience and provide examples relevant to psychology, healthcare and bioethics, law and criminology, information studies, of how brain studies have influenced, are influencing or show the potential to
Christopher D. Chambers +4 more
core +7 more sources
A generalizable definition of chemical similarity for read-across [PDF]
, 2014 Background: Methods that provide a measure of chemical similarity are strongly relevant in several fields of chemoinformatics as they allow to predict the molecular behavior and fate of structurally close compounds.
Benfenati, Emilio +5 more
core +1 more source
Frontiers in Pharmacology, 2017 The lazar framework for read across predictions was expanded for the prediction of nanoparticle toxicities, and a new methodology for calculating nanoparticle descriptors from core and coating structures was implemented.
Christoph Helma +2 more
doaj +1 more source
Journal of Cheminformatics, 2020 Risk assessment of newly synthesised chemicals is a prerequisite for regulatory approval. In this context, in silico methods have great potential to reduce time, cost, and ultimately animal testing as they make use of the ever-growing amount of available
Andrea Morger +7 more
doaj +1 more source
Numerical simulation of neutron radiation effects in avalanche photodiodes [PDF]
, 2000 A new one-dimensional (1-D) device model developed for the simulation of neutron radiation effects in silicon avalanche photodiodes is described. The model uses a finite difference technique to solve the time-independent semiconductor equations across a ...
Hobson, PR, Osborne, M, Watts, SJ
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