Results 111 to 120 of about 535,436 (275)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Levin Visits Anna: The Iconology of Harlotry [PDF]

open access: yes, 1990
Reader response to Anna Karenina has ranged widely over the years, with some inclined to condemn Tolstoy\u27s heroine categorically as a manipulating female and an immoral adulteress.
LeBlanc, Ronald D
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Formalist Criticism and Reader-Response Theory

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics, 2014
The article deals with the interaction of formalism as a trend in language and literature studies, on the one hand, and a teaching method, a technique of teaching to understand and investigate literary text proceeding from its structure and content, on ...
- Mohammad Al Fuadi
doaj  

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Reader Response: <i>D313Y</i> Variant in Fabry Disease: A Systematic Review and Meta-analysis. [PDF]

open access: yesNeurology, 2023
Lackova A   +4 more
europepmc   +1 more source

Транзакційна теорія Луїзи М. Розенблатт: між текстом і читачем [PDF]

open access: yes, 2013
У статті розглянуто транзакційну теорію Луїзи Мішель Розенблатт як певну проміжну ланку між «новою критикою» й теорією читацького відгуку і водночас як самостійну літературознавчу теорію.
Анісімова, Людмила Вікторівна
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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