Results 111 to 120 of about 4,441,099 (286)

Reader-response criticism and hermeneutics [PDF]

open access: yes, 1992
Reader-response criticism approaches to biblical literature in terms of the values, attitudes, and response of readers. The reader, therefore, plays a role in the „production" or „creation" of meaning and significance. This role of the reader relativizes
McKnight Edgar V.
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Formalist Criticism and Reader-Response Theory

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics, 2014
The article deals with the interaction of formalism as a trend in language and literature studies, on the one hand, and a teaching method, a technique of teaching to understand and investigate literary text proceeding from its structure and content, on ...
- Mohammad Al Fuadi
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Fuji Microfiche Reader RFP2

open access: yes, 2010
Microfiche reader in cream plastic housing, lift-up brown perspex cover, mirrored on inside. Cream rocker switch to top. Film fed through slot then projected onto mirror by small lens. Grey flex and three pin plug.
The Betty Smithers Design Collection at Staffordshire University   +1 more
core  

Chasing the shadow: A heuristic look at reader-response. [PDF]

open access: yes, 2006
What is the experience of reader-response from the learner's and teachers' perspectives? The purpose of the research reported here was to explore the students' and teachers' perspectives regarding literature and the reader-response experience adding ...
Harris, Kim A.
core  

Inside Alex’s Mind: Language, Music, and Moral Engagement in A Clockwork Orange

open access: yesMelius: Journal of Narrative and Language Studies
This article examines Anthony Burgess’s A Clockwork Orange through the lens of Reader-Response Theory (Reception Theory, Reader-Oriented Criticism), particularly the perspectives of Wolfgang Iser and Stanley Fish.
Necmettin Kaplan
doaj   +1 more source

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