Results 81 to 90 of about 4,441,099 (286)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Readers' responses

open access: yesTelecommunications Journal of Australia, 2012
Abstract not available.
openaire   +2 more sources

“An Unexpected Sound”: Recognizing Diverse Voices in Postcolonial Literary Interpretation

open access: yesIAFOR Journal of Literature & Librarianship, 2012
This article explores expectations about the ways in which readers from each side of the colonial/colonized divide might approach texts. Pedagogical articles about world and postcolonial literature frequently classify readers in one of two categories ...
Joanne Nystrom Janssen
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Photo Reader

open access: yes, 2010
Photo reader in blue plastic housing, green control button to top. Reader is in two sections which slot together for use. Maker: Storm Technology Inc. Date: 2000 - 2009 - from the The Betty Smithers Design Collection at Staffordshire University.
The Betty Smithers Design Collection at Staffordshire University   +1 more
core  

Cognitive literary Anthropology and Neurohermeneutics. A theoretical Proposal

open access: yesEnthymema, 2017
Following Wolfgang Iser’s studies, literary criticism could no longer avoid a confrontation with the phenomenology of the act of reading. This has led the analysis of a literary text towards new researches regarding the reader’s response theory.
Federica Claudia Abramo   +2 more
doaj   +1 more source

Reader Response: D313Y Variant in Fabry Disease: A Systematic Review and Meta-analysis. [PDF]

open access: yesNeurology, 2023
Bauer P   +4 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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