Results 41 to 50 of about 5,801,512 (242)

Reader-response criticism and hermeneutics [PDF]

open access: yes, 1992
Reader-response criticism approaches to biblical literature in terms of the values, attitudes, and response of readers. The reader, therefore, plays a role in the „production" or „creation" of meaning and significance. This role of the reader relativizes
McKnight Edgar V.
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

The Online Response to the Two Polish Translations of The Wee Free Men by Terry Pratchett

open access: yesPółrocznik Językoznawczy Tertium, 2017
The online community of science fiction and fantasy fans constitutes a rich source of material for analysing reader response to translations as its members often reflect not only on the books they read but also on the quality of their translations. The
Katarzyna Dziemian
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

THE BASIC PRINCIPLES OF EMPIRICISM IN LITERARY THEORY AND CRITICISM: Sources and contemporary empirical researches

open access: yesСинопсис: текст, контекст, медіа, 2013
The article deals with the research of the basic principles of empiricism in Reader-response theory within the environment of American and European literary criticism, beginning with I.A.
Liudmyla V. Anisimova
doaj  

Using Comprehension Questions and Reader-Response Strategies with Second-Semester University Spanish Students

open access: yesBellaterra Journal of Teaching & Learning Language & Literature, 2017
For most of the 20th century, literary criticism has focused on uncovering the author’s intended meanings of a given text. In contrast, reader-response theorists have concentrated on the role of the reader in literary interpretation. This article details
Brian Hibbs
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Reader-Response Criticism: Reader, Response and Interpretation

open access: yes, 2019
© 2019 Karadeniz Technical University. All rights reserved.Reader-response criticism is not a conceptually unified critical position. Its theory is instead associated with the work of critics who use the reading process and response to centralize the ...
BAKTIR, HASAN
core  

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