Results 131 to 140 of about 3,533,611 (280)
Action to protect the independence and integrity of global health research
BMJ Global Health, 2019 David Sanders, Lu Gram, Benjamin Tsofa, Johanne Sundby, Tolib Mirzoev, Kristine Bærøe, Ole Frithjof Norheim, Ejemai Eboreime, Valéry Ridde, Kristine Husøy Onarheim, Emily Mendenhall, Vladimir S Gordeev, Tanya Doherty, Stephen Taylor, David Peters, Shariful Islam, Madhukar Pai, Elysée Nouvet, Francesca L Cavallaro, Shafiu Mohammed, Sassy Molyneux, Karl Blanchet, Janice E Graham, Kayvan Bozorgmehr, David McCoy, Joel Lexchin, Anna-Karin Hurtig, Asha George, Rachel Chapman, Loveday Penn-Kekana, Katerini T Storeng, Dina Balabanova, Veronique Filippi, Sidsel Roalkvam, Grace Akello, Melissa Parker, Jennifer Palmer, Ibukun Abejirinde, Babatope Adebiyi, Clara Affun-Adegbulu, Jhon Álvarez Ahlgren, Ayesha Ahmad, Sameh Al-Awlaqi, Zongo Aloys, Gianna Gayle Amul, Muhammad Asaduzzaman, Akeza Awealom Asgedom, Bouchra Assarag, Nicole Atchessi, Salla Atkins, Okikiolu Badejo, Bailah Molleh, Alessandra Bazzano, Dominique P Béhague, Uli Beisel, Loubna Belaid, Sarah Bernays, Shafi Bhuiyan, Olivia Biermann, Harriet Birungi, Astrid Blystad, Oriane Bodson, Emmanuel Bonnet, Shibaji Bose, Michelle Brear, Rochelle Burgess, Jens Byskov, Séverine Carillon, Sophie Chabeda, Clare Chandler, Francis F Chikuse, Juliana Iwu Chinwe, Beniamino Cislaghi, Svea Closser, Christopher J Colvin, Jenny Cresswell, Fabiana da Cunha Saddi, Judith Daire, Sarah Dalglish, Vincent de Brouwere, Jean-Pierre Olivier de Sardan, Thérèse Delvaux, Annabel Desgrées du Loû, Brahima A Diallo, Aïssa Diarra, Justin Dixon, Alexandre Dumont, Beth Engelbrecht, Susan Erikson, Adama Faye, Sara Fischer, Florence Fournet, Ashley M Fox, Joel Msafiri Francis, Lara Gautier, Lucy Gilson, Sarah Gimbel, Jeff Glenn, Unni Gopinathan, Christoph Gradmann, Giulia Greco, Karen Grepin, Anne Guichard, Pragya Tiwari Gupta, Viveka Guzman, Marte E S Haaland, Anna Häggblom, Amy Hagopian, Karin Hammarberg, Pascal Handschumacher, Katrina Hann, Marie Hasselberg, Natasha Howard, Sameera Hussain, Eleanor Hutchinson, Ezirim Idoteyin, Jennifer J Infanti, Rachel Irwin, Taufique Joarder, Preethi John, Ermel Johnson, Mira Johri, Judith Justice, Charles Kaboré, Kadidiatou Kadio, Matthieu Kamwa, Ann H Kelly, Nora Kenworthy, Sonja Kittelsen, Maren Olene Kloster, Emily Kocsis, Pratap Kumar, Arush Lal, Isabelle Lange, Heather Lanthorn, Frederic Le Marcis, Shelley Lees, Ann Louise Lie, Gojjam Limenih, Isabel Litwin-Davies, Charles Clarke Lodda, Knut Lönnroth, John Manton, Anatole Manzi, Mehr Manzoor, Robert Marten, Mitsuaki Matsui, Allan Mbewe, Esther Mc Sween-Cadieux, Linsey McGoey, Desmond McNeill, Claudio A Méndez, Karen Marie Moland, Zubia Mumtaz, Susan Fairley Murray, Devaki Nambiar, Erica Nelson, Claudia Nieto-Sanchez, Francis Obare, Vincent Okungu, Marit Tolo Østebø, Fatoumata Ouattara, Sachiko Ozawa, Ligia Paina, Rakesh Parashar, Elisabeth Paul, Koen Peeters, Cédric Pennetier, James Pfeiffer, Hanneke Pot, N S Prashanth, Robyn Preston, Antoine de Bengy Puyvallee, Annisa Rahmalia, Simon Reid-Henry, Daniela C Rodríguez, Maya Ronse, Emma Sacks, Oumar Mallé Samb, Eric Sarriot, Inger Brummenæs Scheel, Thomas Schwarz, Kerry Scott, Janet Seeley, Nadine Seward, Geordan Shannon, Jessica Shearer, Katharine Shelley, Kenneth Sherr, Jeremey Shiffman, Frédéric Simard, Neha S Singh, Werner Soors, Rusla Anne Springer, Adrienne Strong, Moses Tetui, Stephanie M Topp, Anne-Marie Turcotte-Tremblay, Chi-Chi Undie, Sara Van Belle, Godelieve Van Heteren, André Janse van Rensburg, Veena Sriram, Sridhar Venkatapuram, Bradley H Wagenaar, Lauren Wallace, David R Walugembe, Oghenebrume Wariri, Alan OBE Whiteside, Bereket Yakob, Scholastica Zakayo, Tony Zitti, Anthony Zwi +212 moredoaj +1 more sourceCorrelation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova +10 morewiley +1 more sourceCircular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk +17 morewiley +1 more sourceBasroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim +4 morewiley +1 more sourceMathematical Economics: A Reader [PDF]
This paper is modeled as a hypothetical first lecture in a graduate Microeconomics or Mathematical Economics Course. We start with a detailed scrutiny of the notion of a utility function to motivate and describe the common patterns across Mathematical ...Aaron Nicholas, Birendra K. Rai1, Chiu Ki So +2 morecore Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan +10 morewiley +1 more source