Results 131 to 140 of about 3,606,096 (290)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Acercamiento al estado actual de la promoción de la lectura en la biblioteca pública en Colombia

open access: yesRevista Interamericana de Bibliotecología, 2008
Se presenta el resultado de la investigación sobre las actividades de promoción de la lectura que realizala biblioteca pública en Colombia. Indaga acerca de la presencia de la biblioteca en la cultura escrita yel rol desempeñado por las iniciativas de ...
Didier Álvarez Zapata   +3 more
doaj  

Gothic Chapbooks and the Urban Reader [PDF]

open access: yes, 2010
This article discusses some principles of Gothic bluebooks and chapbooks. It emphasizes the idea that because of its derivative nature and lack of artistic sophistication, chapbooks were ignored by urban readers. It outlines the views of several scholars,
Hoeveler, Diane
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

THE CONTRADICTORY NATURE OF THE GHOST IN HAMLET [PDF]

open access: yes, 2011
This article explores the contradictory nature of the ghost in Hamlet and shows how Shakespeare seeks to manipulate the reader’s response in Hamlet by using contradictions and ambiguities.
Salami, Ali
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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