Results 41 to 50 of about 1,830,580 (292)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

[Review of] Ellen Carol DuBois and Vicki L. Ruiz, eds. Unequal Sisters: A Multicultural Reader in U. S. Women\u27s History [PDF]

, 1991
Edited by Ellen C. DuBois and Vicki L. Ruiz, two respected historians, Unequal Sisters: A Multicultural Reader in U.S. Women\u27s History is a welcome response to the call for a more complex approach to women\u27s history.
Friaz, Guadalupe
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Reader-Response Criticism

Nalans, 2019
Reader-response criticism is not a conceptually unified critical position. Its theory is instead associated with the work of critics who use the reading process and response to centralize the process of interpretation. The interpretive process delineates
Hasan Baktir
doaj  

Between Fact And Fiction In Dan Brown’s The Da Vinci Code (2003) : Reader Response Analysis [PDF]

, 2015
The research’s purpose is to analyze reader response strategies which are used by the reader to respond Dan Brown’s the Da Vinci Code novel. There are four objectives of the study, first, to know kind of reader response strategies that are applied by the
, Dr. M. Thoyibi, M.S, , Dr. Phil. Dewi Candraningrum, M.Ed., Widodo, Wahyu Unggul   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Wolfgang Iser. Towards Literary Anthropology. Introduction

Enthymema, 2017
In this article you find the editorial remarks of this special issue on “Wolfgang Iser. Towards Literary Anthropology”, edited by Laura Lucia Rossi. Alongside introducing the content of the issue, the author reflects on Wolfgang Iser’s influence and ...
Laura Lucia Rossi
doaj   +1 more source

Immunochromatographic diagnostic test analysis using Google Glass. [PDF]

, 2014
We demonstrate a Google Glass-based rapid diagnostic test (RDT) reader platform capable of qualitative and quantitative measurements of various lateral flow immunochromatographic assays and similar biomedical diagnostics tests.
Caire, Romain, Cortazar, Bingen, Feng, Steve, Ozcan, Aydogan, Turan, Mehmet, Wong, Andrew   +5 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source