Results 41 to 50 of about 6,049,564 (332)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Sortable Elements for Quivers with Cycles [PDF]

, 2009
Each Coxeter element c of a Coxeter group W defines a subset of W called the c-sortable elements. The choice of a Coxeter element of W is equivalent to the choice of an acyclic orientation of the Coxeter diagram of W.
Reading, Nathan, Speyer, David E
core   +2 more sources

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

The effects of listening on speaker and listener while talking about character strengths: an open science school-wide collaboration

Royal Society Open Science
Listening is understood to be a foundational element in practices that rely on effective conversations, but there is a gap in our understanding of what the effects of high-quality listening are on both the speaker and listener.
Tia Moin, Netta Weinstein, Guy Itzchakov, Amanda Branson, Beth Law, Lydia Yee, Emma Pape, Rebecca Y. M. Cheung, Anthony Haffey, Bhismadev Chakrabarti, Philip Beaman   +10 more
doaj   +1 more source

Severe anion gap metabolic acidosis associated with initiation of a very low-carbohydrate diet

Journal of Community Hospital Internal Medicine Perspectives, 2019
Low carbohydrate diets have been popularized as an effective solution for weight loss. Although rare, life-threatening anion gap metabolic acidosis has been reported in patients on these diets.
Sijan Basnet, Niranjan Tachamo, Salik Nazir, Rashmi Dhital, Asad Jehangir, Anthony Donato   +5 more
doaj   +1 more source

Exercise Preferences Among Young Adults: Do Men and Women Want Different Things? [PDF]

, 2018
Background Young adult men are difficult to recruit and retain in lifestyle interventions. This may be in part to gender differences in exercise goals observed in men, but little is known about exercise preferences for young adults, specifically.
LaRose, Jessica Gokee, Reading, Jean M
core   +1 more source

Examining gender differences in young men and women’s goals for a technology-driven weight loss intervention [PDF]

, 2020
Background Emerging adults (EA) are at high risk for weight gain and obesity yet are underrepresented in behavioral weight loss (BWL) programs and fare worse than their older counterparts when they join these programs.
Crane, Melissa M, LaRose, Jessica G, Reading, Jean M   +2 more
core   +1 more source

Assessing direct contributions of morphological awareness and prosodic sensitivity to children’s word reading and reading comprehension [PDF]

, 2018
We examined the independent contributions of prosodic sensitivity and morphological awareness to word reading, text reading accuracy, and reading comprehension. We did so in a longitudinal study of English-speaking children (N = 70).
Andrew John Holliman, Baayen R. H., Carlisle J. F., Elliot C. D., Emily Charlotte Jane Harrison, Field A., Frederickson F., Fudge E. C., Gough P. B., Graeme John Dobson, Hair J. F., Keenan J. M., Nagy W., Snowling M. J., Storm Héléne Deacon, Wood C.   +15 more
core   +3 more sources

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

FEBS Letters, EarlyView.
Accurate protein synthesis is crucial for life. The key players are aminoacyl‐tRNA synthetases (AARSs), which read the genetic code by pairing cognate amino acids and tRNAs. AARSs establish high amino acid selectivity by employing physicochemical limits in molecular recognition.
Igor Zivkovic, Morana Dulic, Ita Gruic‐Sovulj   +2 more
wiley   +1 more source