Results 61 to 70 of about 5,935,938 (300)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
HeliyonGeochemical tracers such as stable isotopes are widely used in groundwater studies for determining aquifer connectivity and groundwater-surface water interactions.
Jim Stanley, Lucy Reading
doaj +1 more source
A robust automated technique for operational calibration of ceilometers using the integrated backscatter from totally attenuating liquid clouds [PDF]
Atmospheric Measurement Techniques, 2019 A simple and robust method for calibrating ceilometers has been tested in an operational environment, demonstrating that the calibrations are stable to better than ±5 % over a period of a year. The method relies on using the integrated backscatter
E. Hopkin +5 more
doaj +1 more source
, 2019 A short review of Deborah Bird Rose's Wild Dog Dreaming (2011) University of Virginia ...
Bhat, Harshavardhan, Bhat, Harshavardhan
core
The politics of the teaching of reading [PDF]
, 2017 Historically, political debates have broken out over how to teach reading in primary schools and infant classrooms. These debates and “reading wars” have often resulted from public concerns and media reportage of a fall in reading standards.
A Luke +34 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
A systematic review of weight-related communication trainings for physicians: What do we know and how can we inform future development of training programs? [PDF]
, 2017 It is reported that physicians lack training to address weight-related concerns with patients. To overcome this, training programs have been implemented in medical settings to prepare physicians to have conversations with patients. However, it is unclear
LaRose, Jessica G +2 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A global climatology of sting-jet extratropical cyclones [PDF]
Weather and Climate DynamicsSting jets have been identified in the most damaging extratropical cyclones impacting northwest Europe. Unlike the cold conveyor belt and other long-lived cyclone wind jets, sting jets can lead to regions of exceptionally strong near-surface winds and ...
S. L. Gray +6 more
doaj +1 more source