Results 61 to 70 of about 2,807,261 (278)

Determination of radon source in basaltic groundwater, using geochemical tracers and chemometric statistical analysis

open access: yesHeliyon
Geochemical tracers such as stable isotopes are widely used in groundwater studies for determining aquifer connectivity and groundwater-surface water interactions.
Jim Stanley, Lucy Reading
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

A robust automated technique for operational calibration of ceilometers using the integrated backscatter from totally attenuating liquid clouds [PDF]

open access: yesAtmospheric Measurement Techniques, 2019
A simple and robust method for calibrating ceilometers has been tested in an operational environment, demonstrating that the calibrations are stable to better than ±5 % over a period of a year. The method relies on using the integrated backscatter
E. Hopkin   +5 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Hypochloraemia and 30 day readmission rate in patients with acute decompensated heart failure

open access: yesESC Heart Failure, 2020
Aims Despite recent advances in guideline‐directed therapy, rehospitalization rates for acute decompensated heart failure (ADHF) remain high. Recently published studies demonstrated the emerging role of hypochloraemia as a predictor of poor outcomes in ...
Roman Marchenko   +7 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A global climatology of sting-jet extratropical cyclones [PDF]

open access: yesWeather and Climate Dynamics
Sting jets have been identified in the most damaging extratropical cyclones impacting northwest Europe. Unlike the cold conveyor belt and other long-lived cyclone wind jets, sting jets can lead to regions of exceptionally strong near-surface winds and ...
S. L. Gray   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

To read or not to read

open access: yesSocial Sciences and Education Research Review, 2020
The act of reading is an elementary cultural technique which, together with writing, has allowed humans to pass on and access information beyond spatial and temporal limitations. Its importance is evident in the many uses and guises given to the verb ‘to read’. For example, the interpretation of other media is often referred to as reading.
openaire   +3 more sources

Thunderstorm occurrence at ten sites across Great Britain over 1884–1993

open access: yesGeoscience Data Journal, 2019
The UK Met Office's Daily Weather Reports (DWR) contain extensive logs of UK thunderstorm activity. To date, only a very small fraction of these data have been digitized as part of the MIDAS dataset, and exclusively after 1950. Using the recently‐scanned
Maria Valdivieso   +5 more
doaj   +1 more source

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