Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Toward a Consensus Model of Cognitive-Reading Achievement Relations Using Meta-Structural Equation Modeling. [PDF]
Hajovsky DB +5 more
europepmc +1 more source
Some teacher preparation institutions may provide higher quality teachers than others. Pupil academic achievement is one measure of the quality of teaching.
Mason, Patrick L.
core
Identifying Effective Classroom Practices Using Student Achievement Data [PDF]
Recent research has confirmed both the importance of teachers in producing student achievement growth and in the variability across teachers in the ability to do that.
Amy L. Wooten +3 more
core
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Not every classroom lifts you up: school academic emphasis, teacher encouragement and motivation, and student constraints in reading achievement-a multilevel latent profile analysis. [PDF]
Turan S.
europepmc +1 more source
Promoting Reading Achievement in Children With Developmental Language Disorders: What Can We Learn From Research on Specific Language Impairment and Dyslexia? [PDF]
Adlof SM.
europepmc +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Do increasing participation rates in early childhood education narrow the reading achievement gap between high- and low-SES primary school students? [PDF]
Steinmann I, Medgyesi M, Symeonaki M.
europepmc +1 more source
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye +11 more
wiley +1 more source

