Results 131 to 140 of about 2,069,613 (288)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Thicker peripapillary choroid may be associated with behavioral factors in Tokyo’s children
Scientific ReportsThe study goals were measurement of the choroidal thickness (CT) and investigation of related factors among children. Third-grade students at an elementary school in Tokyo participated in this study.
Aoba Hashimoto +8 more
doaj +1 more source
ORGANIZATION OF READING CIRCLES IN SCHOOLS
Reading is a fundamental skill that is essential for students to develop throughout their educational careers and beyond. While reading instruction is a core component of elementary education, it is important that secondary schools also foster a culture of reading to help students continue advancing their literacy abilities. One strategy that secondary
openaire +2 more sources
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Workmen's Circle collection, undated, 1903-1993.
Collection consists of material from the administration, services, individual branches, and schools of the Workmen's Circle. The majority of the collection are publications of the Workmen's Circle relating to conventions and education.
Workmen's Circle. +1 more
core
Black and white photo of people, presumably medical staff, sitting in a circle and ...
Modbury Hospital
core +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source