Results 111 to 120 of about 1,838,861 (234)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Multimodal genres in textbooks: are students being schooled for visual literacy?
Bakhtiniana: Revista de Estudos do Discurso, 2012 In this paper, we discuss some issues involved in teaching and learning reading, especially schooling in visual literacy. We seek to observe the work developed with genres that combine verbal and visual languages, found in the reading activities of two ...
Cláudia Graziano Paes de Barros +1 more
doaj
Thoughts of G. Mazzini in “The Circle of Reading” by L.N. Tolstoy
Язык и текстThanks to the earliest Russian translations of Giuseppe Mazzini’s major work, I doveri dell’uomo (The Duties of Man), L.N. Tolstoy became acquainted with the ideas of one of the leading figures of the Italian Risorgimento for whom ...
A. Cavazza
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
The Effects of Literature Circles on Students’ Reading Comprehension Skills
International Journal of Social Science and Human ResearchThis experimental research study was conducted to determine the effects of literature circles on 2nd year baccalaureate students’ reading comprehension skills. The sample consisted of two classes of second year baccalaureate Arts stream students studying at the same public high school.
Ahmed Ait Bella, +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
A DIALOGIC PROPOSAL TO LITERARY LITERACY
Cadernos de Letras da UFF, 2016 Based on Bakhtin’s Circle’ studies, we reflect about a proposal of literary literacy on which teachers can teach abilities on orality, writing, reading and linguistic aspects reflection to their students in an integrated way.
Helio Castelo Branco Ramos
doaj
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source