Results 111 to 120 of about 255,511 (279)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Korelasi Antara Penguasaan Kosakata Siswa Dengan dan Pencapaiannya Dalam Pemahaman Membaca

Cakrawala: Jurnal Pendidikan, 2019
This research deals with the correlation between students vocabulary mastery and their achievement in their reading comprehension. The data were taken from 33 students from class X-TKJ of SMK As Sakienah in Sliyeg The writer used quantitative method by ...
Gina Larassaty
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

THE CORRELATION BETWEEN STUDENTS’ READING ATTITUDE AND THEIR READING COMPREHENSION ACHIEVEMENT

English Community Journal, 2017
This study was aimed at finding out (1)) whether or not there was a significant correlation between students’ reading attitude and their reading comprehension,.
Indah Windra Dwie Agustiani
doaj  

The Reading Strategies and Reading Comprehension of the Health Analyst Department Students [PDF]

, 2016
This research focused on the issue of the reading strategies and reading comprehension of the Health Analyst Department students. The Health Analyst Department students need reading strategies to acquire knowledge according to their specific needs.
Istanto, W. (Wisnu)
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Lessons learnt: Observation of Grade 4 reading comprehension teaching in South African schools across the Progress in International Reading Literacy Study (PIRLS) 2006 achievement spectrum

Reading & Writing, 2014
The evidence of the huge challenges of literacy development faced by South African learners is primarily gleaned from the results of learners’ external assessments.
Lisa Zimmerman
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Applying PQ4R Strategy for Teaching Reading

Indonesian EFL Journal: Journal of ELT, Linguistics, and Literature, 2015
Despite receiving more attention than other language skills in English classroom, the result of students’ reading comprehension achievement is still far from expectation.
Moh.Rodli
doaj   +2 more sources

A Comparative Study of Students’ Reading Comprehension Achievement of Students Thaught Through Retelling Story and Translation [PDF]

, 2013
The objectives of the research are to investigate whether there is significant difference on reading comprehension achievement between students who are taught through Retelling Story and those who are taught through Translation and to find out which one ...
Sudirman, S. (Sudirman), Suparman, U. (Ujang), Yudhistira, T. P. (Tacca)   +2 more
core   +1 more source