Results 61 to 70 of about 2,102,495 (293)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

KWL and Homer\u27s Illiad. [PDF]

open access: yes, 2013
As a student teacher I was disappointed at initial confusion by my World Literature students when we began reading Homer’s Iliad. I wanted to probe my students about the fascinating questions the story raises about the Greek culture, the qualities of a ...
Menke, Kristen
core   +1 more source

Lorenzo Milani in our times [PDF]

open access: yes, 2013
This article pays tribute to one of Europe's foremost critical pedagogues, the Tuscan Don Lorenzo Milani, on the ninetieth anniversary of his birth. It highlights the key moments in his life as priest and educator as well as his pedagogical approach ...
Mayo, Peter
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Cultural features of performance in Norwegian children’s narratives

open access: yesNordisk Barnehageforskning, 2013
This article presents part of a research project whose aim is to investigate Norwegian 6–7-year-old children’s language use in story-telling. The data consist of the children’s oral texts based on a wordless picture book.
Trude Hoel
doaj   +1 more source

Using Portfolios to Develop L2 Cultural Knowledge and Awareness of Students in Intermediate Spanish [PDF]

open access: yes, 1997
In spite of many efforts and contributions from previous researchers, the need for a systematic and consistent approach to teaching culture is still unmet. This pilot study shows that the portfolio is a meaningful way to integrate language and culture in
Lee, Lina
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

An Introduction to Korean Culture for Rehabilitation Service Providers [PDF]

open access: yes, 2001
[Excerpt] The purpose of this monograph is to provide recommendations to busy rehabilitation service providers in the U.S. for effectively working with persons who hold traditional Korean values.
Kim-Rupnow, Weol Soon
core   +1 more source

Reading Culture through Code [PDF]

open access: yes, 2018
The analysis of source code is an emerging approach to interpreting digital texts. This chapter introduces the methodologies of Critical Code Studies (CCS), situates it within the landscape of media and technology studies, and models the interpretive ...
Mark C Marino
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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