Results 41 to 50 of about 28,397 (247)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

De leer, serie radial sobre la promoción de la lectura

Revista Interamericana de Bibliotecología, 2008
Presenta la serie radial De leer, un viaje por la promoción de la lectura, como producto derivado delproyecto de investigación aplicada, realizado en el formato de radio cultural y educativa por laEscuela Interamericana de Bibliotecología, La Emisora ...
Alejandro Uribe-Tirado, Didier Álvarez Zapata, José Roberto Jaramillo Cadavid   +2 more
doaj  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Representaciones bibliotecarias sobre la biblioteca pública, la lectura, el lector, la promoción y la animación a la lectura en Medellín, Colombia Library representations about the Public library, reading, the reader, and promotion and encouragement to reading in Medellin, Colombia

Investigación Bibliotecológica: Archivonomía, Bibliotecología e Información, 2009
El artículo aborda las representaciones bibliotecarias sobre la biblioteca pública, la lectura, el lector, la promoción y la animación a la lectura que tienen los directores y promotores de lectura de las bibliotecas públicas de la ciudad de Medellín ...
Didier Álvarez Zapata, Yicel Nayrobis Giraldo Giraldo, Norfi Yamili Ocampo Molina, Luz Marina Guerra Sierra, Liliana Melgar Estrada, Maricela Gómez Vargas   +5 more
doaj  

Book-Talk: An Activity to Motivate Learners to Read Autonomously in a Foreign Language

Journal of Language and Cultural Education, 2018
In the last decade, extensive reading (ER) had been incorporated into English as a foreign language (EFL) education in various Japanese institutions.
Nishizawa Hitoshi, Yoshioka Takayoshi, Ichikawa Yuri   +2 more
doaj   +1 more source

Legal enforcement of encouragement in local government for employees: essence, problems, and perspectives

Наукові записки НаУКМА: Юридичні науки, 2018
The article researches problems and perspectives of the legal enforcement of local self-government workers encouragement. Problems connected with the insufficient legal regulation of encouragement, in comparison with disciplinary rules, are considered ...
Petro Mozolevskyi
doaj   +1 more source

Perceived Learning Outcomes of Children's Library Instruction Programs: A Case of Parent-child Doctors' Mailbox in National Library [PDF]

Journal of Library and Information Studies, 2017
This study aimed to investigate the implementation methods, process and perceived learning outcomes of children’s library instruction programs. This study adopted a qualitative approach with the Parent-child Doctors’ Mailbox program in National Library ...
Yu-Hua Chang, Hui-Yun Sung
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Reading Habits of University Students in Slovenia: Challenges and the Future of Reading Culture

Knygotyra
The article explores the reading habits of Slovenian university students in teacher education and library science programs, comparing data from two cohorts (2017/18 versus 2024/25).
Miha Kovač, Mojca Kovač Šebart, Jasna Mažgon   +2 more
doaj   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source