Results 111 to 120 of about 2,370,829 (352)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Using Semantic Ambiguity Instruction to Improve Third Graders\u27 Metalinguistic Awareness and Reading Comprehension: An Experimental Study [PDF]

, 2009
An experiment examined whether metalinguistic awareness involving the detection of semantic ambiguity can be taught and whether this instruction improves students\u27 reading comprehension.
Cairns, Helen Smith, Ehri, Linnea C., Zipke, Marcy   +2 more
core   +1 more source

Reading performance, by school practices, academic and social segregation, 2009-15 [PDF]

, 2019
References Abdulkadirog lu, A, Y Che, Y Yasuda, A Abdulkadirog lu, P Pathak, C Walters, J Altonji, C Huang, C Taber, Sandra Black, S Machin, L Boeskens, S Burgess, A Briggs, M Burke, T Sass, Balancing, Equity, D Epple, R Romano, M Urquiola, M Friedman, E Hanushek, E Hanushek, S Link, L Woessmann, E Hanushek, S Rivkin, E Hanushek, L Woessmann, C Hsieh, M Urquiola, H Ladd, E Fiske, H Ladd, E Fiske, N Ruijs, V Lavy, O Silva, F Weinhardt, H Levin, C Lubienski, J Ludwig, P Musset, R Nash, T Nechyba, Raj Chetty, B, B Sacerdote, M Sderstrm, R Uusitalo, M Thrupp, M Urquiola, M Urquiola, M West, L Woessmann, L Woessmann, References Boeskens, L, Le Donn, N, P Musset, Oecd, K Pder, J Valenzuela, C Allende, G Trivelli, References Abdulkadirog lu, A, J Angrist, P Pathak, M Burke, T Sass, W Dobbie, R Fryer, V Lavy, O Silva, F Weinhardt, A Lucas, I Mbiti, S Mendolia, A Paloyo, I Walker, F References Borgonovi, A Pokropek, D Frankel, O Volij, P Givord, C Tavan, E References Hanushek, L Oessmann, References Abdulkadirog lu, A, J Angrist, P Pathak, A Abdulkadirog lu, T Snmez, L Boeskens, G Brunello   +99 more
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Successful transportation of human corneal endothelial tissues without cool preservation in varying Indian tropical climatic conditions and in vitro cell expansion using a novel polymer

Indian Journal of Ophthalmology, 2014
Background: Though the transplantation of human corneal endothelial tissue (CET) separated from cadaver cornea is in practice, its transportation has not been reported.
Srinivas K Rao, John Sudhakar, Periyasamy Parikumar, Sundaram Natarajan, Aditya Insaan, Hiroshi Yoshioka, Yuichi Mori, Shigeo Tsukahara, Subramani Baskar, Sadananda Rao Manjunath, Rajappa Senthilkumar, Paramasivam Thamaraikannan, Thangavelu Srinivasan, Senthilkumar Preethy, Samuel J K Abraham   +14 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

The Enhanced Reading Opportunities Study: Early Impact and Implementation Findings [PDF]

, 2008
This report presents early findings from a demonstration and random assignment evaluation of two supplemental literacy programs that aim to improve the reading comprehension skills and school performance of struggling ninth-grade readers. On average, the
Elizabeth Nelson, James J. Kemple, Kathryn Drummond, Suzannah Herrmann, Terry Salinger, William Corrin   +5 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Ortaokul öğrencilerinde akademik başarı, okuma performansı ve motorik beceri arasındaki ilişkinin incelenmesi

Spormetre Beden Eğitimi ve Spor Bilimleri Dergisi, 2018
Bu araştırmanın amacı, ortaokul öğrencilerinin akademik başarı ve okuma performansları ile motorik becerileri arasındaki ilişkiyi incelemektir. Araştırmaya 5.sınıfta öğrenim gören 100 öğrenci (nerkek=45, nkız=55) katılmıştır.
Umut Canlı, Gözde Ersöz, İlker Özmutlu, Çalık Veli Koçak   +3 more
doaj   +1 more source

Reading Strategies Effect on Reading Comprehension Performance of ESL Learners [PDF]

, 2018
Chiam Kee Swan, Su Luan Wong, Ahmad Fauzi Mohd Ayub, Habsah Hussin   +3 more
openalex   +1 more source