Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Digital Visual Acuity and Reading Performance with Positive and Negative Display Polarities After Bilateral Diffractive Multifocal Intraocular Lens Implantation: A Longitudinal Observational Study. [PDF]
Somkijrungroj T +4 more
europepmc +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Evaluation of reading performance in eyes simulated with different visual acuity and visual field impairment. [PDF]
Peng PL, Hsu WT, Hsu WC.
europepmc +1 more source
Active Home Literacy Environment: parents' and teachers' expectations of its influence on affective relationships at home, reading performance, and reading motivation in children aged 6 to 8 years. [PDF]
Romero-González M +5 more
europepmc +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Joint effects of visual acuity impairment and visual field loss on reading performance: a low-vision simulation in Chinese readers. [PDF]
Luo X +7 more
europepmc +1 more source
Investigating the relationship between students' reading performance, attitudes toward ICT, and economic ability. [PDF]
Sarimanah E +3 more
europepmc +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Development of Crowding Distance in Children Is Faster and Later Than Visual Acuity and Better Predicts Reading Performance. [PDF]
Waugh SJ +3 more
europepmc +1 more source

