Results 101 to 110 of about 802,432 (313)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Practice of Reading Promotion Based on New Media [PDF]
SHS Web of ConferencesWith the new media and other elements deeply rooted in people’s hearts, the innovation-related undertakings related to library management and service are developing vigorously, and the ambitious goals and ideals of “reading for all” and “building a ...
Zhang Shu, Qian Zhenming, Wan Linlin
doaj +1 more source
A Motivational Determinant of Facial Emotion Recognition : Regulatory Focus Affects Recognition of Emotions in Faces [PDF]
, 2014 Funding: The research was supported by The Netherlands Organization for Scientific Research (NWO, project 452-07-006). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer ...
Jarodzka, Halszka +4 more
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
IEEE AccessThis paper presents an AI-driven framework designed to enhance user engagement and optimize catalog management in digital libraries. The framework integrates Variational Autoencoder (VAE)-based personalized recommendations with Adam optimizer and ...
Pinjia Hu, Yichi Zhang
doaj +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
BiD: Textos Universitaris de Biblioteconomia i Documentació, 2019 En aquest article es presenta un recull d'experiències per a promoure la prescripció lectora a la biblioteca Xavier Benguerel de Barcelona que s’han dut a terme durant els darrers cinc anys. S'explica quins són els tipus de fons i els usuaris als quals s'
Azuara González, César +1 more
doaj +1 more source
English Proficiency of Students at Politeknik Negeri Balikpapan Based on TOEIC [PDF]
, 2020 English language proficiency is generally measured by English competency scores such as TOEFL and TOEIC. To be able to apply the right learning patterns for students of Politeknik Negeri Balikpapan (Poltekba) for the purpose of mastering the TOEIC, an ...
Damayanti, L. (Lilik), Gafur, A. (Abdul)
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