Results 41 to 50 of about 158,391 (248)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The Short-Term Effect of Caffeine Consumption on Reading Performance

open access: yesJournal of Health Science and Medical Research (JHSMR)
Objective: Caffeine, a widely consumed psychoactive substance, is recognized for its cognitive-enhancing effects, notably enhancing performance on tasks requiring narrative comprehension, where it has been shown to boost both acuity and speed. This study
Alia Natasha Nazarudin   +2 more
doaj   +1 more source

Influence of road traffic noise peaks on reading task performance and disturbance in a laboratory context

open access: yesActa Acustica, 2022
The influence of fluctuating road traffic noise on perceived disturbance during a reading task as well as on performance, inside a living room with closed windows, is presented in this paper.
Lavandier Catherine   +4 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Contrast and font affect reading speeds of adolescents with and without a need for language-based learning support [PDF]

open access: yesTraining, Language and Culture, 2017
This pre-study investigates the effects of the font type and the contrast between the colour of the text and the colour of the background on the reading speed of readers a) with different age groups and b) with a different need for language-based ...
Heiner Böttger   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Speed of Reading Instructions for Creative Task Performance: Influence of Typography and Reading Media

open access: yesApplied Sciences
Teachers often serve as creators of written instructions that students use to complete assignments. This research investigates whether the speed at which the instructions are read is impacted by different visual designs (such as typeface shape, colour ...
Marija Toure   +2 more
doaj   +1 more source

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