Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Ensuring Success for Young Children: Early Childhood Literacy [PDF]
, 2009 Outlines issues in early childhood literacy and provides a discussion guide for funders on strategies for supporting early childhood literacy programs, community engagement, and closing the reading proficiency gap among the disadvantaged and ...
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Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
THE TEACHERS’ STRATEGIES IN OVERCOMING STUDENTS’ DIFFICULTIES IN COMPREHENDING NARRATIVE TEXTS (Descriptive study at MTs Ash – Shiddiqiyah and MTs Al – Hidayah Cirebon) [PDF]
, 2014 Bilqis Himayatun. 1410130126: The Teachers’ Strategies in Overcoming Students’ Difficulties in Comprehending Narrative Texts (Descriptive study at MTs Ash – Shiddiqiyah and MTs Al – Hidayah Cirebon) This research investigated the teachers‟ strategies ...
BILQIS HIMAYATUN,
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Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Identifying reading strategies using latent semantic analysis: Comparing semantic benchmarks [PDF]
, 2004 Keith Millis +5 more
openalex +1 more source
Cogent EducationAbstractThis research examined the impact of explicit reading strategy training on Ethiopian university students’ reading strategy use and critical reading ability in the English as a Foreign Language (EFL) context. Two intact classes, a control group (n = 35) and an experimental group (n = 45), participated in the study.
Asalifew Mekuria +2 more
openaire +2 more sources
The Relationship between Reading Strategies and Reading Achievement of the EFL Students
International Journal of Instruction, 2020 Leonardus Par
semanticscholar +1 more source
ESL students’ online and offline reading strategies: scrolling, clicking, flipping and reading / Izyani Mohamad Zaki, Fauziah Hassan and Abu Bakar Mohamed Razali [PDF]
, 2008 In this borderless world, computers and the Internet have become important tools of communication and learning and they have also become an important part of our lives.
Hassan, Fauziah +2 more
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Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source