Results 161 to 170 of about 403,191 (312)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Guidelines for developing and strengthening K-12 reading programs Reaching for treasures: instructional strategies for implementing reading treasures Instructional strategies for implementing reading treasures

open access: yes, 1988
Phase I. Guidelines for Developing and Strengthening K-12 Reading Programs -- Acknowledgments -- Appendix A: Philosophy of Reading -- Appendix B: K-12 Reading Curriculum Guide -- Appendix C: Suggested Instructional Resources -- Glossary of Reading Terms -
Kansas State Department of Education, Division of Education Services, Educational Assistance Section
core  

IMPROVING STUDENTS’ READING COMPREHENSION THROUGH SEMANTIC MAPPING STRATEGY ( An Action Research in the Eighth Year Students of SMPN 1 Sine in the 2009/2010 Academic Year ) [PDF]

open access: yes, 2010
Language is a means of communication. Communication takes place not only with two or more speakers, but also between a speaker and a text. There should be a kind of interaction between the learner ( reader ) and the text which is being read in ...
Muhtar, Kamal
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Strategies and Techniques for Teaching Children with Learning Disabilities: A Case Study of the Spring Reading Program

open access: yes, 2015
This case study explored strategies and techniques in order to assist individuals with learning disabilities in their academic achievement. Of particular focus was how a literacy-based program, titled The Spring Reading Program, utilizes effective ...
Cowan, Hope
core  

An investigation of guided reading with beginning readers in the national literacy strategy (1998-2002) [PDF]

open access: yes, 2004
This thesis reports a research investigation into teachers' practices in, and perceptions of, guided reading in the National Literacy Strategy. The study was framed by two connected debates.
McKay, Mary R., McKay, Mary R
core  

Surveying Metacognitive Reading Strategies Awareness of Fifth-Semester English Department Students

open access: yesEnglish Education Journal: Jurnal Pengembangan Pendidikan dan Pengembangan Pengajaran Bahasa, 2019
This article serves result on the survey for metacognitive awareness level of reading strategies use in academic reading by English department students of Syiah Kuala University (Unsyiah), Banda Aceh.
Dina Damayanti   +2 more
doaj  

Strategies in teaching reading: key strategies in fiction reading

open access: yes
Fiction reading plays a pivotal role in language acquisition by improving reading comprehension and fostering critical thinking. Despite its educational significance, the Swedish national tests suggest that many pupils lack basic reading comprehension skills, therefore it affects their motivation to read and their overall academic performance.
openaire   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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