Results 71 to 80 of about 1,934,051 (281)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A Toolkit of Motivational Skills: How to Help Others Reach for Change [PDF]

open access: yes, 2019
A Toolkit of Motivational Skills, Third Edition, draws on the latest research to show how the Motivational Interviewing approach can be effectively utilized to draw out and sustain an individual’s internal motivation for behavioral change.
Fuller, Catherine   +2 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Computer graphics techniques for modeling page turning [PDF]

open access: yes, 2007
Turning the page is a mechanical part of the cognitive act of reading that we do literally unthinkingly. Interest in realistic book models for digital libraries and other online documents is growing.
Liesaputra, Veronica, Witten, Ian H.
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Improving Reading Comprehension and Fluency in an Intellectually Disabled Student: A Case Study

open access: yesAnkara Üniversitesi Eğitim Bilimleri Fakültesi Özel Eğitim Dergisi
Introduction: We can quickly access information in the modern world. Therefore, it is critical to concurrently improve reading fluency and comprehension skills.
Özgül Güler Bülbül
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

PENGARUH TEKNIK MEMBACA SQ3R TERHADAP MEMBACA PEMAHAMAN MAHASISWA FKIP UNIVERSITAS BUNG HATTA PADANG

open access: yesTa'dib, 2019
The main issue discussed in this article is the students’ low interest in reading textbooks. In addition, students do not use various techniques. As a result, they feel bored, and less concentrated when reading.
Gusnetti Gusnetti   +3 more
doaj  

Reading Hidden Writing and Drawings on Papyrus Using Speckle Optical Technique and Multispectral Images

open access: green, 2022
Leandro Buffarini   +5 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

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