In situ monitoring of environmental water quality using an autonomous microfluidic sensor [PDF]
, 2010 An autonomous microfluidic sensor for phosphate in environmental waters has been developed and assessed in laboratory and field trials. The sensor is based on the molybdenum yellow method for phosphate detection in which a phosphate-containing sample is ...
Cleary, John +3 more
core +1 more source
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
Detection of nitrite by flow injection analysis using a novel paired emitter-detector diode (PEDD) as a photometric detector [PDF]
, 2007 An inexpensive flow injection analysis system for determining low concentration levels of nitrite employing the Griess reagent spectrophotometric method is reported.
Diamond, Dermot +3 more
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Treatment of laundrette wastewater using Starbon and Fenton's reagent [PDF]
, 2016 The use of grey water for a variety of purposes is gaining increased popularity as a means of preserving scarce freshwater resources. In this work, catalytic oxidation over Fenton's reagent and adsorption techniques using Starbon (mesoporous material ...
Clark, James H. +2 more
core +1 more source
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
Capillary Agglutination Technology [PDF]
, 2006 In medical diagnostic tests, including pregnancy testing and tests for typed red blood cells, a small fluid sample is placed at one end of a capillary channel, which has been lined with a dried reagent.
Breward, Chris, Richardson, Giles
core
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Phage Display Analysis of Monoclonal Antibody Binding to Anthrax Toxin Lethal Factor
Toxins, 2017 AVR1674 and AVR1675 are monoclonal antibodies (mAbs) that bind with high specificity to anthrax toxin lethal factor (LF) and lethal toxin (LTx).
Jason M. Goldstein +6 more
doaj +1 more source
ORGANIC CHEMICAL REAGENTS. IV. THE PREPARATION OF ALKYL IODIDES.2 [PDF]
, 1919 Roger Adams, Van Voorhees
openalex +1 more source