Results 171 to 180 of about 1,853,765 (343)

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

open access: yesFEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr   +5 more
wiley   +1 more source

In-house reagent for creatinine in Synchron CX-3 delta

open access: yesJournal of Health Science and Medical Research (JHSMR), 2008
An in-house reagent for the determination of creatinine inserum was prepared and evaluated using the Beckman Synchron CX-3 delta automatic analyzer. The reagent was compared with the commercially available reagent.
P Choosongsang   +4 more
doaj  

Deoxygenation of organic nitrites [PDF]

open access: yes
Organic nitrites deoxygenated in presence of tervalent phosphorus ...
Boyer, J. H., Woodyard, J. D.
core   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

open access: yesFEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson   +5 more
wiley   +1 more source

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

open access: yesFEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli   +4 more
wiley   +1 more source

AROMATIC SULFONIC ACIDS AS REAGENTS FOR AMINO ACIDS

open access: hybrid, 1942
William H. Stein   +4 more
openalex   +1 more source

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