Results 191 to 200 of about 1,853,765 (343)

Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

FEBS Open Bio, EarlyView.
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki, Hiroki Okanishi, Yoshikatsu Kanai, Ryoji Masui   +3 more
wiley   +1 more source

Application of Anti-Immune Complex Reagents in Small Molecule Analyte Immunoassays

ACS Omega
Kai Du, Haihua He, Lan Zhao, Li Gao, Tinghua Li   +4 more
doaj   +1 more source

Impact of maximal overexpression of a non-toxic protein on yeast cell physiology. [PDF]

Elife
Fujita Y, Namba S, Kamada Y, Moriya H.
europepmc   +1 more source

Heat of Formation of the Grignard Reagent, CH3Mgl: Ether [PDF]

, 1950
A. S. Carson, H. A. Skinner
openalex   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source

Uronium from X-ray-Desorbed Urea Enables Sustainable Ultrasensitive Detection of Amines and Semivolatiles. [PDF]

Anal Chem
Shcherbinin A, Finkenzeller H, Partovi F, Vinkvist N, Kontro J, Boyer M, Mikkilä J, Iyer S, Mikkilä J, Juuti P, Sarnela N, Kangasluoma J, Rissanen M.   +12 more
europepmc   +1 more source

On a new reagent for ascertaining the presence of sugar in certain liquids [PDF]

M. Maumené
openalex   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Derivative-Based Non-Target Identification of DNA-Reactive Impurities with Fragment Ion Filtering. [PDF]

Molecules
Zhang D, Hang B, Zhang Y, You P, Shi F, Gong L.   +5 more
europepmc   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source