Results 261 to 270 of about 1,853,765 (343)
A MORE SPECIFIC REAGENT FOR THE DETERMINATION OF SUGAR IN URINE
James B. Sumner
openalex +1 more source
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann +6 more
wiley +1 more source
A genome-wide association study implicates the olfactory system in <i>Drosophila melanogaster</i> diapause-associated lifespan extension and fecundity. [PDF]
Easwaran S, Montell DJ.
europepmc +1 more source
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard +15 more
wiley +1 more source
Ogremorphin inhibits GPR68 mediated MUC5AC expression. [PDF]
Neitzel LR +3 more
europepmc +1 more source
ON THE MECHANISM OF ENZYME INHIBITION BY SULFHYDRYL REAGENTS
Thomas P. Singer
openalex +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Synthesis of Pandaroside D from <i>Pandaros acanthifolium</i> via Construction of a Rare Enone System in the Steroid D Ring. [PDF]
Michalak K +3 more
europepmc +1 more source
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers +3 more
wiley +1 more source

