Results 21 to 30 of about 1,215,916 (294)
Mirror-image streptavidin with specific binding to L-biotin, the unnatural enantiomer
The streptavidin–biotin system is known to have a very high affinity and specificity and is widely used in biochemical immunoassays and diagnostics. However, this method is affected by endogenous D-biotin in serum sample measurements (biotin interference)
Masatoshi Suganuma +9 more
doaj +1 more source
Clinically Important Phleboviruses and Their Detection in Human Samples
The detection of phleboviruses (family: Phenuiviridae) in human samples is challenged by the overall diversity and genetic complexity of clinically relevant strains, their predominantly nondescript clinical associations, and a related lack of awareness ...
Amy J. Lambert, Holly R. Hughes
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Characterization a polyurethane-based reactive hot melt adhesive for applications in materials
In the present study, we used tensile shear tests, Shore hardness tests, differential scanning calorimetry (DSC), and thermogravimetry (TGA) to characterize a reactive polyurethane-based hot melt adhesive.
JOSE LUDDEY MARULANDA AREVALO +3 more
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IntroductionRecent breakthroughs in genomics have facilitated the identification of single nucleotide polymorphisms (SNPs) and small insertions-deletions (InDels).
Yawo Mawunyo Nevame Adedze +12 more
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Francisco Pereira Lobo, Giovanni Marques de Castro, and Felipe Campelo are part of an international team of collaborators that developed CALANGO, a comparative genomics tool to investigate quantitative genotype-phenotype relationships.
Giovanni Marques de Castro +2 more
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The clinical utility of antigen test using anterior nasal samples has not been well evaluated. We conducted a prospective study in a drive-through testing site located at a PCR center to evaluate the diagnostic performance of the antigen test QuickNavi ...
Yuto Takeuchi +9 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Rapid development of neutralizing and diagnostic SARS-COV-2 mouse monoclonal antibodies
The need for high-affinity, SARS-CoV-2-specific monoclonal antibodies (mAbs) is critical in the face of the global COVID-19 pandemic, as such reagents can have important diagnostic, research, and therapeutic applications.
Asheley P. Chapman +21 more
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Dosage enzymatique en flux continu du glycerol dans les vins
Un procédé de détermination du glycérol dans les vins blancs et les vins rouges est décrit. Les réactifs nécessaires sont la glycérokinase, la glycérol déhydrogénase, le NAD, l'ATP et une solution tampon à pH 9,8 contenant de l'hydrazine.
Jean-Louis Batlle, Y. Collon
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