Results 191 to 200 of about 34,349 (240)

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen   +12 more
wiley   +1 more source

Cuproptosis and Disulfidptosis Converge to Empower PD‐L1 Checkpoint Therapy via Cadict‐Induced PD‐L1 Translation

open access: yesAdvanced Science, EarlyView.
This study introduces Cadict, an EGFR‐targeted nanodrug that co‐delivers cuproptosis and disulfidptosis inducers to overcome immune resistance. Cadict synergistically enhances tumor cytotoxicity and sensitizes cancers to ICIs by upregulating PD‐L1 via an Eif5b‐dependent translation mechanism, fostering a potent antitumor immune response and ...
Shaoqing Huang   +12 more
wiley   +1 more source

Engineered Nanobodies for early and accurate diagnosis of dengue virus infection. [PDF]

open access: yesPLoS Negl Trop Dis
Pavan MF   +12 more
europepmc   +1 more source

Considerations of Flow Cytometric Lymphocyte Subset Analysis in Korea Based on a Survey of Current Clinical Laboratory Practice. [PDF]

open access: yesAnn Lab Med
Park M   +10 more
europepmc   +1 more source

Multiplexed detection of febrile infections using CARMEN. [PDF]

open access: yesNat Commun
Kamariza M   +20 more
europepmc   +1 more source

Development of a Chemiluminescence Immunoassay for the Serological Diagnosis of Sheep and Bovine Brucellosis. [PDF]

open access: yesMicroorganisms
Yan X   +13 more
europepmc   +1 more source

Multicenter performance evaluation of the "quanty TOXO (RH region)" kit (Clonit) for molecular diagnosis of toxoplasmosis. [PDF]

open access: yesJ Clin Microbiol
Nourrisson C   +8 more
europepmc   +1 more source

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