Results 241 to 250 of about 65,650 (304)

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source

Danggui Buxue Decoction and Its Active Constituents Inhibit Drug-Induced Uterine Contractions via L-Type Calcium Channels and the IP₃/Ca²⁺ Pathway. [PDF]

Pharmaceuticals (Basel)
Liu M, He T, An W, Guo P, Zhou T, Chen Y, Tian X, Wu M, Zhang T, Zhang S.   +9 more
europepmc   +1 more source

CandyCollect open-to-closed (O2C) microfluidic system for rapid and user-centric detection of group A <i>Streptococcus</i>.

Lab Chip
Leong KM, Sanchez JC, Craig C, Tatka JA, Arvizu RR, Robertson IH, Shinkawa VAM, Robinson TR, Chang MM, Su X, Thongpang S, Theberge AB, Berthier E, Olanrewaju AO.   +13 more
europepmc   +1 more source

Triggered "Capture-and-Release" Enables a High-Affinity Rebinding Strategy for Sensitivity Enhancement in Lateral Flow Assays. [PDF]

ACS Sens
Ho C, McMahon C, Ayrton JP, Chudasama V, Thomas MR.   +4 more
europepmc   +1 more source

Integrated Microfluidic Giant Magnetoresistance (GMR) Biosensor Platform for Magnetoresistive Immunoassay of Myoglobin. [PDF]

Biosensors (Basel)
Wang Y, Wang H, Zhang Y, Cui S, Hu F, Li B.   +5 more
europepmc   +1 more source

Sensitive and Facile Detection of Aloin via N,F-CD-Coated Test Strips Coupled with a Miniaturized Fluorimeter. [PDF]

Biomolecules
Wei G, Wang C, Wang R, Zhang P, Geng X, Li J, Ostovan A, Chen L, Song Z.   +8 more
europepmc   +1 more source

Development and proof-of-concept evaluation for a low resource compatible Chikungunya virus diagnostic. [PDF]

PLoS Negl Trop Dis
Balea R, Amarilla AA, Hobson-Peters J, Macdonald J, Suhrbier A, Kasimov VM, Watterson D, Pollak NM, McMillan DJ.   +8 more
europepmc   +1 more source

Urinary Reagent Strip: A Reliable and Rapid Bedside Diagnostic Tool for Meningitis. [PDF]

Cureus
Hussain N, Khan RU, Farooq A, Mati A.
europepmc   +1 more source

Adapting antibody-invertase fusion protein immunoassays to multiwell plates for infectious disease antibody quantification.

Sens Diagn
Ornelas-Gatdula E, An X, Spangler JB, Arroyo-Currás N.   +3 more
europepmc   +1 more source