Results 111 to 120 of about 559,455 (353)

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

History of visual systems in the Systems Engineering Simulator [PDF]

open access: yes
The Systems Engineering Simulator (SES) houses a variety of real-time computer generated visual systems. The earliest machine dates from the mid-1960's and is one of the first real-time graphics systems in the world.
Christianson, David C.
core   +1 more source

Computer graphics techniques for modeling page turning [PDF]

open access: yes, 2007
Turning the page is a mechanical part of the cognitive act of reading that we do literally unthinkingly. Interest in realistic book models for digital libraries and other online documents is growing.
Liesaputra, Veronica, Witten, Ian H.
core   +1 more source

Rejection-Cascade of Gaussians: Real-time adaptive background subtraction framework

open access: yes, 2019
Background-Foreground classification is a well-studied problem in computer vision. Due to the pixel-wise nature of modeling and processing in the algorithm, it is usually difficult to satisfy real-time constraints. There is a trade-off between the speed (
B Valentine, BR Kiran, J Zuo, T Bouwmans
core   +1 more source

Estimating Illumination Direction for Augmented Reality in Real-Time by using Low-Cost Sensors

open access: yesJournal of Computer Science and Technology, 2017
In recent years, Augmented Reality has become a very popular topic, both as a research and commercial field. This trend has originated with the use of mobile devices as computational core and display.
Kevin E. Soulier   +2 more
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Real-time graphics for the Space Station Freedom cupola, developed in the Systems Engineering Simulator [PDF]

open access: yes
Among the Lyndon B. Johnson Space Center's responsibilities for Space Station Freedom is the cupola. Attached to the resource node, the cupola is a windowed structure that will serve as the space station's secondary control center.
Hess, Philip W., Red, Michael T.
core   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

open access: yesMolecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul   +11 more
wiley   +1 more source

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