Results 61 to 70 of about 28,061 (262)
Visualization of the complex double-outlet right ventricle anatomy using real-time three-dimensional computer graphics [PDF]
, 2023 Akiharu Omori +2 more
openalex +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Reducing redundancy of real time computer graphics in mobile systems [PDF]
, 2018 Enrique de Lucas
openalex +2 more sources
APPROPRIATENESS OF USING 3D GRAPHICS WHEN TRAINING MILITARY SPECIALISTS
Sučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2014 Problems of financing with Armed Forces of Ukraine cause necessity of application productive and cost-effective methods of military specialists training.
Anatolii Y. Dereviyanchuk +1 more
doaj
Realistic 3D Simulators for Automotive: A Review of Main Applications and Features
SensorsRecent advancements in vehicle technology have stimulated innovation across the automotive sector, from Advanced Driver Assistance Systems (ADAS) to autonomous driving and motorsport applications.
Ivo Silva +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Accelerating Berends–Giele recursion for gluons in arbitrary dimensions over finite fields
European Physical Journal C: Particles and FieldsThis work provides a proof of concept for the computation of pure gluonic amplitudes in quantum chromodynamics (QCD) on graphics processing units (GPUs). The implementation relies on the Berends–Giele recursion algorithm and, for the first time on a GPU,
Juan Cruz-Martinez +2 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source