Results 71 to 80 of about 395,953 (326)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Real-Time Simulation of a Cerebellar Scaffold Model on Graphics Processing Units

open access: yesFrontiers in Cellular Neuroscience, 2021
Large-scale simulation of detailed computational models of neuronal microcircuits plays a prominent role in reproducing and predicting the dynamics of the microcircuits. To reconstruct a microcircuit, one must choose neuron and synapse models, placements,
Rin Kuriyama   +4 more
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

APPLICATION TECHNIQUE OF COMPUTER GRAPHICS FOR NONSTEADY PROCESSES RESEARCH IN MODERN MATERIAL SCIENCE

open access: yesAdvanced Engineering Research, 2011
The application technique of computer graphics for processing the experimental data in the mode of real time is presented. The data are received in the research practice of modern material science.
Victor N. Pustovoit   +2 more
doaj  

Development of Real-Time Dual-Display Handheld and Bench-Top Hybrid-Mode SD-OCTs

open access: yesSensors, 2014
Development of a dual-display handheld optical coherence tomography (OCT) system for retina and optic-nerve-head diagnosis beyond the volunteer motion constraints is reported.
Nam Hyun Cho   +5 more
doaj   +1 more source

Computer simulations and real-time control of ELT AO systems using graphical processing units [PDF]

open access: yesSPIE Proceedings, 2012
The adaptive optics (AO) simulations at the Thirty Meter Telescope (TMT) have been carried out using the efficient, C based multi-threaded adaptive optics simulator (MAOS, http://github.com/lianqiw/maos). By porting time-critical parts of MAOS to graphical processing units (GPU) using NVIDIA CUDA technology, we achieved a 10 fold speed up for each GTX ...
Wang, Lianqi, Ellerbroek, Brent
openaire   +4 more sources

Perceptually optimized real-time computer graphics [PDF]

open access: yes, 2012
Perceptual optimization, the application of human visual perception models to remove imperceptible components in a graphics system, has been proven effective in achieving significant computational speedup.
Smith, Jeffrey
core   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

APPLICATION TECHNIQUE OF COMPUTER GRAPHICS FOR NONSTEADY PROCESSES RESEARCH IN MODERN MATERIAL SCIENCE

open access: yesВестник Донского государственного технического университета, 2018
The application technique of computer graphics for processing the experimental data in the mode of real time is presented. The data are received in the research practice of modern material science.
Victor N. Pustovoit   +2 more
doaj  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

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