Results 111 to 120 of about 1,158,517 (169)

Development of Nanoflare Nanosensors for Monitoring Cellular Insulin mRNA in Beta Cells and Islets

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents the design and application of In2‐NF probes for detecting insulin mRNA in beta cells and islets. Using spherical nucleic acid‐coated gold nanoparticles, the probes offer strong fluorescent signals upon hybridization. Their performance is validated across 2D and 3D cultures and rat islets, demonstrating sensitive, real‐time mRNA ...
Yana Hu   +7 more
wiley   +1 more source

Evaluation of the Truenat® chip-based real-time PCR platform for infectious disease diagnostics. [PDF]

open access: yesPract Lab Med
Rebello Pinho JR   +14 more
europepmc   +1 more source

Magnetic Droplet Manipulation on Open Surfaces

open access: yesAdvanced Materials Technologies, EarlyView.
Recent advances in the manipulation of magnetic droplets demonstrate various manipulations on open surfaces, including transport, splitting, merging, and force‐controlled motion, enabled by magnetic particles and external fields. ABSTRACT Manipulation of liquids on a smaller scale enables applications in various fields, particularly diagnostics and ...
Robab Jahangir, Vahid Nasirimarekani
wiley   +1 more source

Buckling‐Driven Linearity in Flexible Capacitive Pressure Sensors Based on a Three‐Dimensional Dual‐Pore Polyurethane Structure

open access: yesAdvanced Materials Technologies, EarlyView.
A flexible pressure sensor utilizing a 3D dual‐pore polyurethane structure is developed to overcome the intrinsic trade‐off between sensitivity and linearity. By inducing sequential buckling through distinct pore sizes and shapes, the device achieves highly linear and sensitive responses across a wide pressure range.
Jae Yeong Jang, Jaemin Choi, Young Jung
wiley   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang   +13 more
wiley   +1 more source

Evaluation of mdh, dld, tcfA, and folE gene markers for detection of enteric fever using real-time PCR. [PDF]

open access: yesSci Rep
Arshad S   +7 more
europepmc   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

open access: yesAdvanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy