Results 101 to 110 of about 19,571,554 (293)

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Troubleshooting Real-Time PCR Screening for Leishmania infantum

Journal of Arthropod-Borne Diseases, 2018
Troubleshooting Real-Time PCR Screening for Leishmania ...
Philippe Gil de MENDONCA
doaj   +1 more source

HUMAN HERPESVIRUS 8 UPREGULATES ACTIVATING TRANSCRIPTION FACTOR 4 (ATF4) and REAL TIME PCR TO ASSESS TOTAL BACTERIAL LOAD IN CHRONIC WOUNDS. [PDF]

, 2010
I. Human Herpesvirus 8 Upregulates Activator Transcription Factor 4 BACKGROUND: Human herpesvirus 8 (HHV-8) is the primary etiologic agent of Kaposi’s sarcoma, a highly vascularised neoplasm of endothelial origin characterized by inflammation ...
Gentili, Valentina
core  

Real-Time PCR final

, 2014
Real-Time PCR quantification of E74B, phm and ...
Alexander W. Shingleton (196929), Shingleton, Alexander W., Takashi Koyama (417981), Alekos Athanasiadis (70850), Mirth, Christen K., Marisa A. Rodrigues (3268659), Koyama, Takashi, Athanasiadis, Alekos, Christen K. Mirth (580295), Rodrigues, Marisa A.   +9 more
core   +1 more source

Effect of solute stress and temperature on growth rate and TRI5 gene expression using real time RT-PCR in Fusarium graminearum from Spanish wheat [PDF]

, 2010
The objective of this work was to study the effect of ecophysiological factors on trichothecene gene expression and growth in Fusarium graminearum.
Magan, Naresh, González-Jaén, María Teresa, Marín, Patricia, Jurado, Miguel, Vázquez, Covadonga   +4 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Real-Time PCR Assay for Quantitative Mismatch Detection

BioTechniques, 2003
We describe here a quantitative realtime PCR assay for the detection of single-base-pair differences that does not require fluorescently labeled gene-specific probes or complicated primer combinations.
L. Shively, L. Chang, J.M. LeBon, Q. Liu, A.D. Riggs, J. Singer-Sam   +5 more
doaj   +1 more source

Development of a Real Time PCR method for GMO detection in soy lecithin

, 2022
reservedFin dall’antichità piante e animali che presentavano caratteristiche desiderabili venivano selezionati dall’uomo per portare avanti le generazioni future.
CAMPANELLA, LISA
core  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Enumeration of Mycobacterium leprae using real-time PCR.

PLoS Neglected Tropical Diseases, 2008
Mycobacterium leprae is not cultivable in axenic media, and direct microscopic enumeration of the bacilli is complex, labor intensive, and suffers from limited sensitivity and specificity. We have developed a real-time PCR assay for quantifying M. leprae
Richard W Truman, P Kyle Andrews, Naoko Y Robbins, Linda B Adams, James L Krahenbuhl, Thomas P Gillis   +5 more
doaj   +1 more source