Results 241 to 250 of about 19,571,554 (293)

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Clinical and Molecular Diagnostic Profiling of Vaginitis Using Multiplex Real-Time PCR: A Multicenter Study. [PDF]

Diagnostics (Basel)
Mai HT, Nguyen CC, Vo HTN, Nguyen TTB, Pham TT, Ngo HT, Ngo XT, Bui ATP, Ta HTK, Nguyen ATV.   +9 more
europepmc   +1 more source

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

Development and preliminary evaluation of real-time PCR assays for six lactic acid bacteria. [PDF]

Sci Rep
Li SJ, Cui B, Li W, Lu F, Yuan L, Luo K, He S, Lu W, Xu K, Zhu X, Sun X, Xie Y, Han L, Zheng Y, Qian L, Ou S, Zhang G, Yang C.   +17 more
europepmc   +1 more source

Genome‐Wide In Vivo RNAi Screening Identifies HOXD4 as a Tumor Metastasis Suppressor in Colorectal Cancer

Advanced Science, EarlyView.
Metastasis remains a major challenge in colorectal cancer. Using an in vivo shRNA screening system, this study identifies Homeobox D4 as a key metastasis suppressor. Reduced Homeobox D4 expression is associated with aggressive tumor features. Functional and mechanistic analyses show that it inhibits epithelial‐mesenchymal transition by repressing ...
Zhi‐hua Ye, Wen‐jing Luo, Lu Li, Wen‐di Shuai, Ling Zhou, You‐fa Duan, Xue Chen, Jun‐kai Zhang, Wenlin Huang, Ran‐yi Liu   +9 more
wiley   +1 more source

Real-Time PCR Detection of <i>Alicyclobacillus acidoterrestris</i> in Fruit Juice: Method Validation and Implications for Guaiacol-Related Spoilage. [PDF]

Foods
Lin SL, Valdrez MM, Chang SH.
europepmc   +1 more source

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Advanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang, Ruiqi Sun, Yang Fu, Zhonghan Wu, Xinyu Tong, Hong Tang, Wentao Zhao, Zhi Liang, Jintao Zheng, Yanan Guan, Ke Zhou, Penghong Song, Shusen Zheng, Hangxiang Wang, Haiyang Xie   +14 more
wiley   +1 more source

Assay for numerical and graphical detection of Native American mitochondrial haplogroup B with real-time PCR. [PDF]

Mol Biol Rep
Ramírez-Molina RM, García-Ortiz H, González-Oliver A.   +2 more
europepmc   +1 more source

A Sensitive Real-Time PCR-Based Assay for the Identification of <i>Colletotrichum</i> in Phytosanitary and Clinical Applications. [PDF]

J Fungi (Basel)
Phurbu D, Duan W, Crous PW, Cai L, Liu F.   +4 more
europepmc   +1 more source

Detection of Certain Berries in Difficult Samples by Singleplex and Multiplex Real-Time PCR-HRM: A Case Study of Pitfalls. [PDF]

Methods Protoc
Fialova L, Marova I.
europepmc   +1 more source