Results 171 to 180 of about 760,834 (347)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Reconstruction of 3D crystal growth from transmission optical microscopy images. [PDF]

open access: yesPNAS Nexus
Ilett TP   +5 more
europepmc   +1 more source

Real-time Level-of-Detail Strand-based Hair Rendering [PDF]

open access: green
Huang Tao   +5 more
openalex   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

SimTac: A Physics-Based Simulator for Vision-Based Tactile Sensing with Biomorphic Structures. [PDF]

open access: yesCyborg Bionic Syst
Zhang X   +7 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

An API-Level Frame Workload Model for Real-Time Rendering Applications

open access: gold, 2020
Iman Soltani Mohammadi   +2 more
openalex   +1 more source

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