Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian +9 more
wiley +1 more source
A ROS-Based Online System for 3D Gaussian Splatting Optimization: Flexible Frontend Integration and Real-Time Refinement. [PDF]
Wang L, Xu J, An X, Ji Y, Wu Y, Ma Z.
europepmc +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Trends and Techniques in 3D Reconstruction and Rendering: A Survey with Emphasis on Gaussian Splatting. [PDF]
Chen W, Li Z, Guo J, Zheng C, Tian S.
europepmc +1 more source
YOLO-NR: Neural Re-Rendering andMulti-Granularity Fusion for Real-Time SmallObject Detection
Muhammad Aon +2 more
openalex +1 more source
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu +11 more
wiley +1 more source
The construction of an integrated cloud network digital intelligence platform for rail transit based on artificial intelligence. [PDF]
Wang K, Zhou X, Guan J.
europepmc +1 more source
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu +5 more
wiley +1 more source
GPU-accelerated deformation mapping in hybrid organ models for real-time simulation. [PDF]
Miyazaki R, Hayashi Y, Oda M, Mori K.
europepmc +1 more source

