Results 31 to 40 of about 3,518,526 (296)

Drugs: Real World Outcomes [PDF]

Drugs - Real World Outcomes, 2014
It is our great pleasure to welcome you to Drugs: Real World Outcomes, the latest offering from Adis that targets research involving the use of real-world data. We all know that the gold standard in research is the randomized controlled clinical trial; however, we all also know that these trials by the nature of their design fail to inform clinicians ...
Peters, Dene C., van Rensburg, Anton
openaire   +2 more sources

A ‘Real-World’ Assignment for History Students [PDF]

, 2020
In the last issue of the Bulletin I wrote something of a polemic on the need for history departments to do more to encourage better employment outcomes for our students, both undergraduate and graduate.
Talbot, Robert J.
core   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Health-related quality of life and productivity burden for non-professional caregivers of adults with rare diseases: a real-world study

Orphanet Journal of Rare Diseases
Background Rare diseases present a substantial patient burden, but the impact on non-professional caregivers is poorly understood. We explored the health-related quality of life (HRQoL) and productivity burden on caregivers of adults with rare diseases ...
Ben Johnson, Gregor Gibson, Daniel Baskerville, Giorgio Castellano, Jonathan de Courcy, Halima Iqbal, James Piercy, Angela Williams, Rafael Pinedo-Villanueva, Angela Rylands   +9 more
doaj   +1 more source

Multiplicative Attribute Graph Model of Real-World Networks [PDF]

, 2010
Large scale real-world network data such as social and information networks are ubiquitous. The study of such social and information networks seeks to find patterns and explain their emergence through tractable models. In most networks, and especially in
Kim, Myunghwan, Leskovec, Jure
core   +3 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Factors driving decisions in the use of HIV pre-exposure prophylaxis: a real-world study in the United States

HIV Research & Clinical Practice
Background: Uptake of pre-exposure prophylaxis (PrEP) in the United States (US) remains below target, despite reported high efficacy in prevention of HIV infection and being considered as a strategy for ending new HIV transmissions.
Yohance Whiteside, Abigail McMillan, Fritha Hennessy, Phoebe Salmon, Tim Holbrook, Bekana K. Tadese   +5 more
doaj   +1 more source

Short and long-term costs among women experiencing preterm labour or preterm birth: the German experience

BMC Pregnancy and Childbirth, 2018
Background Preterm labour and birth (PTL/PTB) is characterised by major health and developmental risks for children, life–changing consequences for their families, and substantial healthcare and economic challenges for wider society.
Shibani Pokras, Jeanne Pimenta, Evie Merinopoulou, Dimitra Lambrelli   +3 more
doaj   +1 more source

Impact of chronic kidney disease and anemia on health-related quality of life and work productivity: analysis of multinational real-world data

BMC Nephrology, 2020
Background Reductions in health-related quality of life (HRQoL) in patients with chronic kidney disease (CKD) are thought to be exacerbated by the low hemoglobin (Hb) levels that define anemia, a common complication of CKD. The current analysis evaluated
Heleen van Haalen, James Jackson, Bruce Spinowitz, Gary Milligan, Rebecca Moon   +4 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source