Results 1 to 10 of about 6,061,294 (414)

Strategies to Address Current Challenges in Real-World Evidence Generation in Japan

Drugs - Real World Outcomes, 2023
The generation of real-world evidence (RWE), which describes patient characteristics or treatment patterns using real-world data (RWD), is rapidly growing more popular as a tool for decision-making in Japan.
Thomas Laurent, Dimitra Lambrelli, Ryozo Wakabayashi, Takahiro Hirano, Ryohei Kuwatsuru   +4 more
doaj   +1 more source

Incidence, costs and post-operative complications following ankle fracture – A US claims database analysis

BMC Musculoskeletal Disorders, 2022
Background The epidemiology and payer costs for ankle fractures are not well documented. This study evaluated: (1) the incidence of ankle fracture and ankle surgery following fracture in the US population; and (2) the clinical presentation of patients ...
Mari F. Vanderkarr, Jill W. Ruppenkamp, Mollie Vanderkarr, Anjani Parikh, Chantal E. Holy, Matthew Putnam   +5 more
doaj   +1 more source

Validation of algorithms to identify colorectal cancer patients from administrative claims data of a Japanese hospital

BMC Health Services Research, 2023
Background Administrative claims data are a valuable source for clinical studies; however, the use of validated algorithms to identify patients is essential to minimize bias.
Takahiro Hirano, Makiko Negishi, Yoshiki Kuwatsuru, Masafumi Arai, Ryozo Wakabayashi, Naoko Saito, Ryohei Kuwatsuru   +6 more
doaj   +1 more source

Health Canada & Canadian Society for Pharmaceutical Sciences - Use of Real World Data/Evidence to Inform Regulatory Decision Making

Journal of Pharmacy & Pharmaceutical Sciences, 2020
Real world data (RWD) and real world evidence (RWE) are playing increasing roles in health-care decisions. Real world data are routinely employed to support reimbursement and coverage decisions for drugs and devices.
Real World Data Workshop Group CSPS/Health Canada
doaj   +1 more source

Factors associated with physician-reported treatment status of patients with osteoarthritis pain

BMC Musculoskeletal Disorders, 2022
Background Osteoarthritis (OA) is typically associated with pain, but many patients are not treated. Methods This point in time study explored factors associated with treatment status, using logistic regression of data from the Adelphi OA Disease ...
Thomas J. Schnitzer, Rebecca L. Robinson, Leslie Tive, Joseph C. Cappelleri, Andrew G. Bushmakin, James Jackson, Mia Berry, Sophie Barlow, Chloe Walker, Lars Viktrup   +9 more
doaj   +1 more source

Impact of "time zero" of Follow-Up Settings in a Comparative Effectiveness Study Using Real-World Data with a Non-user Comparator: Comparison of Six Different Settings

Drugs - Real World Outcomes, 2022
Background Time-related bias can lead to misleading conclusions. Properly setting the "time zero" of follow-up is crucial for avoiding these biases. However, the time-zero setting is challenging when comparing users and non-users of a study drug because ...
Ryozo Wakabayashi, Takahiro Hirano, Thomas Laurent, Yoshiki Kuwatsuru, Ryohei Kuwatsuru   +4 more
doaj   +1 more source

The impact of national centralized drug procurement on health expenditures for lung cancer inpatients: A difference-in-differences analysis in a large tertiary hospital in China

Frontiers in Public Health, 2022
The availability and affordability of medicines remain major health challenges around the world. In March 2019, the Chinese government introduced a pilot National Centralized Drug Procurement (NCDP) program in order to reduce drug prices and improve the ...
Yuan-jin Zhang, Yuan-jin Zhang, Yuan-jin Zhang, Yuan-jin Zhang, Yan Ren, Yan Ren, Yan Ren, Yan Ren, Quan Zheng, Jing Tan, Jing Tan, Jing Tan, Jing Tan, Ming-hong Yao, Ming-hong Yao, Ming-hong Yao, Ming-hong Yao, Yun-xiang Huang, Yun-xiang Huang, Yun-xiang Huang, Yun-xiang Huang, Xia Zhang, Xia Zhang, Xia Zhang, Xia Zhang, Kang Zou, Kang Zou, Kang Zou, Kang Zou, Shao-yang Zhao, Xin Sun, Xin Sun, Xin Sun, Xin Sun   +33 more
doaj   +1 more source

The add-on effects of Danhong injection among patients with ischemic stroke receiving Western medicines: A systematic review and meta-analysis

Frontiers in Pharmacology, 2022
Background: Danhong injection is widely used for treating ischemic stroke in China. However, its effects on ischemic stroke patients when given along with Western medicines (i.e., the add-on effect) were not well-established.Methods: We searched PubMed ...
Yu Ma, Yu Ma, Yu Ma, Ke Deng, Ke Deng, Ke Deng, Jiali Liu, Jiali Liu, Jiali Liu, Bin Ma, Fan Mei, Wen Hui, Xiaochao Luo, Xiaochao Luo, Xiaochao Luo, Minghong Yao, Minghong Yao, Minghong Yao, Yanmei Liu, Yanmei Liu, Yanmei Liu, Xuan Qin, Xuan Qin, Xuan Qin, Xu Zhou, Kang Zou, Kang Zou, Kang Zou, Ling Li, Ling Li, Ling Li, Xin Sun, Xin Sun, Xin Sun   +33 more
doaj   +1 more source

Asthma control among treated US asthma patients in Practice Fusion’s electronic medical record research database

npj Primary Care Respiratory Medicine, 2023
This study investigated burden of ‘not well-controlled’ asthma, overall and by Global Initiative for Asthma (GINA) Step, among treated asthma patients in Practice Fusion’s research database.
Jonathan Davitte, Bailey DeBarmore, David Hinds, Shiyuan Zhang, Jessica Chao, Leah Sansbury   +5 more
doaj   +1 more source

The Association of Real-World CA 19-9 Level Monitoring Patterns and Clinical Outcomes Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Frontiers in Oncology, 2021
BackgroundPancreatic cancer is expected to be the third deadliest cancer in the US in 2021. Evaluation of treatment response in patients with mPDAC necessitates scheduled clinical and radiographic assessments along with monitoring serum CA 19-9 levels ...
Ben George, Matthew Kent, Andy Surinach, Neil Lamarre, Paul Cockrum   +4 more
doaj   +1 more source